FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020513372> ?p ?o ?g. }

• W2020513372 abstract "In positron emission tomography (PET) studies with radioligands for neuroreceptors, tracer kinetics have been described by the standard two-tissue compartment model that includes the compartments of nondisplaceable binding and specific binding to receptors. In the present study, we have developed a new graphic plot analysis to determine the total distribution volume (V(T)) and nondisplaceable distribution volume (V(ND)) independently, and therefore the binding potential (BP(ND)). In this plot, Y(t) is the ratio of brain tissue activity to time-integrated arterial input function, and X(t) is the ratio of time-integrated brain tissue activity to time-integrated arterial input function. The x-intercept of linear regression of the plots for early phase represents V(ND), and the x-intercept of linear regression of the plots for delayed phase after the equilibrium time represents V(T). BP(ND) can be calculated by BP(ND)=V(T)/V(ND)-1. Dynamic PET scanning with measurement of arterial input function was performed on six healthy men after intravenous rapid bolus injection of [(11)C]FLB457. The plot yielded a curve in regions with specific binding while it yielded a straight line through all plot data in regions with no specific binding. V(ND), V(T), and BP(ND) values calculated by the present method were in good agreement with those by conventional non-linear least-squares fitting procedure. This method can be used to distinguish graphically whether the radioligand binding includes specific binding or not." @default.
• W2020513372 created "2016-06-24" @default.
• W2020513372 creator A5005318923 @default.
• W2020513372 creator A5011325858 @default.
• W2020513372 creator A5026216076 @default.
• W2020513372 creator A5031586548 @default.
• W2020513372 creator A5033868555 @default.
• W2020513372 creator A5044712859 @default.
• W2020513372 creator A5050027882 @default.
• W2020513372 creator A5058646333 @default.
• W2020513372 creator A5060847562 @default.
• W2020513372 creator A5061784822 @default.
• W2020513372 creator A5085556975 @default.
• W2020513372 date "2010-01-01" @default.
• W2020513372 modified "2023-10-08" @default.
• W2020513372 title "A new graphic plot analysis for determination of neuroreceptor binding in positron emission tomography studies" @default.
• W2020513372 cites W1528617091 @default.
• W2020513372 cites W189146960 @default.
• W2020513372 cites W1965036463 @default.
• W2020513372 cites W1986159971 @default.
• W2020513372 cites W2003090874 @default.
• W2020513372 cites W2014469558 @default.
• W2020513372 cites W2015024017 @default.
• W2020513372 cites W2017273367 @default.
• W2020513372 cites W2017409452 @default.
• W2020513372 cites W2027885955 @default.
• W2020513372 cites W2051228374 @default.
• W2020513372 cites W2063017390 @default.
• W2020513372 cites W2067068908 @default.
• W2020513372 cites W2080362180 @default.
• W2020513372 cites W2081843002 @default.
• W2020513372 cites W2087070363 @default.
• W2020513372 cites W2088898864 @default.
• W2020513372 cites W2091088809 @default.
• W2020513372 cites W2092078486 @default.
• W2020513372 cites W2092111603 @default.
• W2020513372 cites W2103630323 @default.
• W2020513372 cites W2121887890 @default.
• W2020513372 cites W2296611393 @default.
• W2020513372 cites W2339958462 @default.
• W2020513372 cites W373488126 @default.
• W2020513372 cites W659306929 @default.
• W2020513372 doi "https://doi.org/10.1016/j.neuroimage.2009.07.021" @default.
• W2020513372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19631754" @default.
• W2020513372 hasPublicationYear "2010" @default.
• W2020513372 type Work @default.
• W2020513372 sameAs 2020513372 @default.
• W2020513372 citedByCount "8" @default.
• W2020513372 countsByYear W20205133722012 @default.
• W2020513372 countsByYear W20205133722013 @default.
• W2020513372 countsByYear W20205133722014 @default.
• W2020513372 countsByYear W20205133722017 @default.
• W2020513372 crossrefType "journal-article" @default.
• W2020513372 hasAuthorship W2020513372A5005318923 @default.
• W2020513372 hasAuthorship W2020513372A5011325858 @default.
• W2020513372 hasAuthorship W2020513372A5026216076 @default.
• W2020513372 hasAuthorship W2020513372A5031586548 @default.
• W2020513372 hasAuthorship W2020513372A5033868555 @default.
• W2020513372 hasAuthorship W2020513372A5044712859 @default.
• W2020513372 hasAuthorship W2020513372A5050027882 @default.
• W2020513372 hasAuthorship W2020513372A5058646333 @default.
• W2020513372 hasAuthorship W2020513372A5060847562 @default.
• W2020513372 hasAuthorship W2020513372A5061784822 @default.
• W2020513372 hasAuthorship W2020513372A5085556975 @default.
• W2020513372 hasConcept C105795698 @default.
• W2020513372 hasConcept C107824862 @default.
• W2020513372 hasConcept C112705442 @default.
• W2020513372 hasConcept C113196181 @default.
• W2020513372 hasConcept C121332964 @default.
• W2020513372 hasConcept C126322002 @default.
• W2020513372 hasConcept C136229726 @default.
• W2020513372 hasConcept C139254425 @default.
• W2020513372 hasConcept C167651023 @default.
• W2020513372 hasConcept C185544564 @default.
• W2020513372 hasConcept C185592680 @default.
• W2020513372 hasConcept C2775842073 @default.
• W2020513372 hasConcept C2778863792 @default.
• W2020513372 hasConcept C2908944559 @default.
• W2020513372 hasConcept C2989005 @default.
• W2020513372 hasConcept C33923547 @default.
• W2020513372 hasConcept C43617362 @default.
• W2020513372 hasConcept C46141821 @default.
• W2020513372 hasConcept C48921125 @default.
• W2020513372 hasConcept C55493867 @default.
• W2020513372 hasConcept C60592354 @default.
• W2020513372 hasConcept C67847695 @default.
• W2020513372 hasConcept C71924100 @default.
• W2020513372 hasConceptScore W2020513372C105795698 @default.
• W2020513372 hasConceptScore W2020513372C107824862 @default.
• W2020513372 hasConceptScore W2020513372C112705442 @default.
• W2020513372 hasConceptScore W2020513372C113196181 @default.
• W2020513372 hasConceptScore W2020513372C121332964 @default.
• W2020513372 hasConceptScore W2020513372C126322002 @default.
• W2020513372 hasConceptScore W2020513372C136229726 @default.
• W2020513372 hasConceptScore W2020513372C139254425 @default.
• W2020513372 hasConceptScore W2020513372C167651023 @default.
• W2020513372 hasConceptScore W2020513372C185544564 @default.
• W2020513372 hasConceptScore W2020513372C185592680 @default.
• W2020513372 hasConceptScore W2020513372C2775842073 @default.
• W2020513372 hasConceptScore W2020513372C2778863792 @default.

• next