FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020531213> ?p ?o ?g. }

• W2020531213 abstract "Abstract 3-deoxysilybin (3-DS), also known as (–)-isosilandrin A, is a natural flavonoid of Silybum marianum. This study was designed to investigate the anti-inflammatory effect and the underlying molecular mechanisms of 3-DS in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. 3-DS dose-dependently inhibited the production of NO and the expression of iNOS in LPS-stimulated RAW264.7 macrophages. 3-DS also inhibited the production of pro-inflammatory cytokines (MCP-1, TNF-α, IL-6, and IL-1β) in LPS-stimulated RAW264.7 macrophages. Moreover, 3-DS decreased the NF-κB DNA binding activity in LPS-stimulated RAW264.7 macrophages. Furthermore, 3-DS suppressed NF-κB activation by inhibiting the degradation of IκBα and nuclear translocation of p65 subunit of NF-κB in LPS-stimulated RAW264.7 macrophages. Taken together, the present study suggests for the first time that 3-DS may exhibit an anti-inflammatory effect through the suppression of NF-κB transcriptional activation in LPS-stimulated RAW264.7 macrophages." @default.
• W2020531213 created "2016-06-24" @default.
• W2020531213 creator A5032097450 @default.
• W2020531213 creator A5045075813 @default.
• W2020531213 creator A5057599101 @default.
• W2020531213 creator A5062462909 @default.
• W2020531213 creator A5070634880 @default.
• W2020531213 creator A5071224429 @default.
• W2020531213 date "2014-12-02" @default.
• W2020531213 modified "2023-10-17" @default.
• W2020531213 title "3-deoxysilybin exerts anti-inflammatory effects by suppressing NF-κB activation in lipopolysaccharide-stimulated RAW264.7 macrophages" @default.
• W2020531213 cites W1824652155 @default.
• W2020531213 cites W1987522619 @default.
• W2020531213 cites W1990742692 @default.
• W2020531213 cites W1998770222 @default.
• W2020531213 cites W2011391958 @default.
• W2020531213 cites W2020032281 @default.
• W2020531213 cites W2022025132 @default.
• W2020531213 cites W2028692318 @default.
• W2020531213 cites W2031355173 @default.
• W2020531213 cites W2050994594 @default.
• W2020531213 cites W2055311718 @default.
• W2020531213 cites W2057080021 @default.
• W2020531213 cites W2059726407 @default.
• W2020531213 cites W2066171146 @default.
• W2020531213 cites W2069531297 @default.
• W2020531213 cites W2077963343 @default.
• W2020531213 cites W2083963118 @default.
• W2020531213 cites W2090944931 @default.
• W2020531213 cites W2100664574 @default.
• W2020531213 cites W2120241246 @default.
• W2020531213 cites W2122984623 @default.
• W2020531213 cites W2138819828 @default.
• W2020531213 cites W2167096600 @default.
• W2020531213 cites W4246077736 @default.
• W2020531213 cites W4246131648 @default.
• W2020531213 cites W4255669922 @default.
• W2020531213 doi "https://doi.org/10.1080/09168451.2014.948377" @default.
• W2020531213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25105683" @default.
• W2020531213 hasPublicationYear "2014" @default.
• W2020531213 type Work @default.
• W2020531213 sameAs 2020531213 @default.
• W2020531213 citedByCount "14" @default.
• W2020531213 countsByYear W20205312132014 @default.
• W2020531213 countsByYear W20205312132016 @default.
• W2020531213 countsByYear W20205312132017 @default.
• W2020531213 countsByYear W20205312132018 @default.
• W2020531213 countsByYear W20205312132019 @default.
• W2020531213 countsByYear W20205312132020 @default.
• W2020531213 countsByYear W20205312132021 @default.
• W2020531213 countsByYear W20205312132022 @default.
• W2020531213 crossrefType "journal-article" @default.
• W2020531213 hasAuthorship W2020531213A5032097450 @default.
• W2020531213 hasAuthorship W2020531213A5045075813 @default.
• W2020531213 hasAuthorship W2020531213A5057599101 @default.
• W2020531213 hasAuthorship W2020531213A5062462909 @default.
• W2020531213 hasAuthorship W2020531213A5070634880 @default.
• W2020531213 hasAuthorship W2020531213A5071224429 @default.
• W2020531213 hasBestOaLocation W20205312131 @default.
• W2020531213 hasConcept C104317684 @default.
• W2020531213 hasConcept C123298856 @default.
• W2020531213 hasConcept C138626823 @default.
• W2020531213 hasConcept C153911025 @default.
• W2020531213 hasConcept C164027704 @default.
• W2020531213 hasConcept C17991360 @default.
• W2020531213 hasConcept C185592680 @default.
• W2020531213 hasConcept C202751555 @default.
• W2020531213 hasConcept C203014093 @default.
• W2020531213 hasConcept C2776914184 @default.
• W2020531213 hasConcept C2777730290 @default.
• W2020531213 hasConcept C2778754761 @default.
• W2020531213 hasConcept C2779244956 @default.
• W2020531213 hasConcept C2779730028 @default.
• W2020531213 hasConcept C2780210117 @default.
• W2020531213 hasConcept C55493867 @default.
• W2020531213 hasConcept C59822182 @default.
• W2020531213 hasConcept C62478195 @default.
• W2020531213 hasConcept C86339819 @default.
• W2020531213 hasConcept C86803240 @default.
• W2020531213 hasConcept C95444343 @default.
• W2020531213 hasConcept C98270193 @default.
• W2020531213 hasConceptScore W2020531213C104317684 @default.
• W2020531213 hasConceptScore W2020531213C123298856 @default.
• W2020531213 hasConceptScore W2020531213C138626823 @default.
• W2020531213 hasConceptScore W2020531213C153911025 @default.
• W2020531213 hasConceptScore W2020531213C164027704 @default.
• W2020531213 hasConceptScore W2020531213C17991360 @default.
• W2020531213 hasConceptScore W2020531213C185592680 @default.
• W2020531213 hasConceptScore W2020531213C202751555 @default.
• W2020531213 hasConceptScore W2020531213C203014093 @default.
• W2020531213 hasConceptScore W2020531213C2776914184 @default.
• W2020531213 hasConceptScore W2020531213C2777730290 @default.
• W2020531213 hasConceptScore W2020531213C2778754761 @default.
• W2020531213 hasConceptScore W2020531213C2779244956 @default.
• W2020531213 hasConceptScore W2020531213C2779730028 @default.
• W2020531213 hasConceptScore W2020531213C2780210117 @default.
• W2020531213 hasConceptScore W2020531213C55493867 @default.
• W2020531213 hasConceptScore W2020531213C59822182 @default.
• W2020531213 hasConceptScore W2020531213C62478195 @default.
• W2020531213 hasConceptScore W2020531213C86339819 @default.

• next