FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020532037> ?p ?o ?g. }

• W2020532037 endingPage "135" @default.
• W2020532037 startingPage "129" @default.
• W2020532037 abstract "The effects of tungsten carbide nanoparticles (nano-WC) on the properties of voltage-dependent potassium currents and evoked action potentials were studied in the hippocampal CA1 pyramidal neurons of rats at the ages of postnatal days 10-14 using the whole-cell patch-clamp technique. The results indicated that: (1) the amplitudes of transient outward potassium current (I(A)) and delayed rectifier potassium current (I(K)) were significantly decreased by 10(-7) g/ml nano-WC, while the current-voltage curves of I(A) and I(K) were significantly decreased by nano-WC from +10 to +90 mV. (2) Nano-WC produced a depolarizing shift in the steady-state activation curve of I(A) and I(K) with increased slope factors, and delayed the recovery of I(A) from inactivation, but no significant effects were found on the inactivation of I(A). (3) Nano-WC prolonged the evoked action potential duration and lowered the firing rate. These results suggest that 10(-7) g/ml nano-WC can decrease the amplitudes of I(A) and I(K) currents by reducing the opening number of voltage-gated potassium channels and delaying the recovery of I(A) from inactivation, which indicate that nano-WC has the potential neurotoxicity." @default.
• W2020532037 created "2016-06-24" @default.
• W2020532037 creator A5023805779 @default.
• W2020532037 creator A5030306649 @default.
• W2020532037 creator A5041144560 @default.
• W2020532037 creator A5070222700 @default.
• W2020532037 date "2012-03-01" @default.
• W2020532037 modified "2023-09-26" @default.
• W2020532037 title "Inhibitory effect of tungsten carbide nanoparticles on voltage-gated potassium currents of hippocampal CA1 neurons" @default.
• W2020532037 cites W1967134520 @default.
• W2020532037 cites W1977419340 @default.
• W2020532037 cites W1989040608 @default.
• W2020532037 cites W1995581686 @default.
• W2020532037 cites W2004472644 @default.
• W2020532037 cites W2006297115 @default.
• W2020532037 cites W2033300348 @default.
• W2020532037 cites W2041195114 @default.
• W2020532037 cites W2061008935 @default.
• W2020532037 cites W2069527452 @default.
• W2020532037 cites W2069676796 @default.
• W2020532037 cites W2070032514 @default.
• W2020532037 cites W2072049042 @default.
• W2020532037 cites W2072353704 @default.
• W2020532037 cites W2096065654 @default.
• W2020532037 cites W2104789245 @default.
• W2020532037 cites W2107811195 @default.
• W2020532037 cites W2113700116 @default.
• W2020532037 cites W2115123250 @default.
• W2020532037 cites W2117890656 @default.
• W2020532037 cites W2122368908 @default.
• W2020532037 cites W2129852583 @default.
• W2020532037 cites W2334476312 @default.
• W2020532037 cites W4234143025 @default.
• W2020532037 doi "https://doi.org/10.1016/j.toxlet.2011.12.001" @default.
• W2020532037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22192952" @default.
• W2020532037 hasPublicationYear "2012" @default.
• W2020532037 type Work @default.
• W2020532037 sameAs 2020532037 @default.
• W2020532037 citedByCount "22" @default.
• W2020532037 countsByYear W20205320372013 @default.
• W2020532037 countsByYear W20205320372014 @default.
• W2020532037 countsByYear W20205320372015 @default.
• W2020532037 countsByYear W20205320372016 @default.
• W2020532037 countsByYear W20205320372017 @default.
• W2020532037 countsByYear W20205320372018 @default.
• W2020532037 countsByYear W20205320372019 @default.
• W2020532037 countsByYear W20205320372020 @default.
• W2020532037 countsByYear W20205320372021 @default.
• W2020532037 countsByYear W20205320372022 @default.
• W2020532037 crossrefType "journal-article" @default.
• W2020532037 hasAuthorship W2020532037A5023805779 @default.
• W2020532037 hasAuthorship W2020532037A5030306649 @default.
• W2020532037 hasAuthorship W2020532037A5041144560 @default.
• W2020532037 hasAuthorship W2020532037A5070222700 @default.
• W2020532037 hasConcept C12554922 @default.
• W2020532037 hasConcept C126322002 @default.
• W2020532037 hasConcept C147944092 @default.
• W2020532037 hasConcept C148762608 @default.
• W2020532037 hasConcept C170493617 @default.
• W2020532037 hasConcept C178790620 @default.
• W2020532037 hasConcept C185592680 @default.
• W2020532037 hasConcept C2781422231 @default.
• W2020532037 hasConcept C4141045 @default.
• W2020532037 hasConcept C517785266 @default.
• W2020532037 hasConcept C542268612 @default.
• W2020532037 hasConcept C55493867 @default.
• W2020532037 hasConcept C71924100 @default.
• W2020532037 hasConcept C83743174 @default.
• W2020532037 hasConcept C86803240 @default.
• W2020532037 hasConceptScore W2020532037C12554922 @default.
• W2020532037 hasConceptScore W2020532037C126322002 @default.
• W2020532037 hasConceptScore W2020532037C147944092 @default.
• W2020532037 hasConceptScore W2020532037C148762608 @default.
• W2020532037 hasConceptScore W2020532037C170493617 @default.
• W2020532037 hasConceptScore W2020532037C178790620 @default.
• W2020532037 hasConceptScore W2020532037C185592680 @default.
• W2020532037 hasConceptScore W2020532037C2781422231 @default.
• W2020532037 hasConceptScore W2020532037C4141045 @default.
• W2020532037 hasConceptScore W2020532037C517785266 @default.
• W2020532037 hasConceptScore W2020532037C542268612 @default.
• W2020532037 hasConceptScore W2020532037C55493867 @default.
• W2020532037 hasConceptScore W2020532037C71924100 @default.
• W2020532037 hasConceptScore W2020532037C83743174 @default.
• W2020532037 hasConceptScore W2020532037C86803240 @default.
• W2020532037 hasIssue "2" @default.
• W2020532037 hasLocation W20205320371 @default.
• W2020532037 hasLocation W20205320372 @default.
• W2020532037 hasOpenAccess W2020532037 @default.
• W2020532037 hasPrimaryLocation W20205320371 @default.
• W2020532037 hasRelatedWork W1972920546 @default.
• W2020532037 hasRelatedWork W1990054546 @default.
• W2020532037 hasRelatedWork W1994630059 @default.
• W2020532037 hasRelatedWork W2022996845 @default.
• W2020532037 hasRelatedWork W2088281397 @default.
• W2020532037 hasRelatedWork W2108333597 @default.
• W2020532037 hasRelatedWork W2155353284 @default.
• W2020532037 hasRelatedWork W2227486288 @default.
• W2020532037 hasRelatedWork W2355882656 @default.

• next