FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020532704> ?p ?o ?g. }

• W2020532704 endingPage "12057" @default.
• W2020532704 startingPage "12053" @default.
• W2020532704 abstract "Aromatic L-amino acid decarboxylase (AADC, EC 4.1.1.28) catalyzes the decarboxylation of L-dopa to dopamine in catecholamine cells and 5-hydroxytryptophan to serotonin in serotonin-producing neurons. This enzyme is also expressed in relatively large quantities in nonneuronal tissues such as liver and kidney, where its function is unknown. Neuronal and nonneuronal tissues express AADC mRNAs with distinct 5' untranslated regions. To understand how this is accomplished at the genomic level, we have isolated rat genomic DNA encoding AADC. The organization of the AADC gene suggests that there are two separate promoters specific for the transcription of neuronal and nonneuronal forms of the AADC message. A small exon containing 68 bases of the neuronal-specific 5' end is located approximately 9.5 kilobases upstream of the translation start site, which is contained in the third exon. Approximately 7 kilobases upstream from the neuron-specific promoter is another small exon containing 71 bases of the 5' end of the nonneuronal AADC message. These data suggest that transcription initiating at distinct promoters, followed by alternative splicing, is responsible for the expression of the neuronal and nonneuronal forms of the AADC message." @default.
• W2020532704 created "2016-06-24" @default.
• W2020532704 creator A5016887845 @default.
• W2020532704 creator A5022318117 @default.
• W2020532704 creator A5027270763 @default.
• W2020532704 creator A5045786825 @default.
• W2020532704 creator A5088480931 @default.
• W2020532704 date "1992-12-15" @default.
• W2020532704 modified "2023-10-16" @default.
• W2020532704 title "Distinct promoters direct neuronal and nonneuronal expression of rat aromatic L-amino acid decarboxylase." @default.
• W2020532704 cites W1559736216 @default.
• W2020532704 cites W1566143315 @default.
• W2020532704 cites W1909977507 @default.
• W2020532704 cites W1917300031 @default.
• W2020532704 cites W1965164352 @default.
• W2020532704 cites W1965367679 @default.
• W2020532704 cites W1969600436 @default.
• W2020532704 cites W1970587959 @default.
• W2020532704 cites W1978881490 @default.
• W2020532704 cites W1985014772 @default.
• W2020532704 cites W1991201530 @default.
• W2020532704 cites W1997456725 @default.
• W2020532704 cites W2002955373 @default.
• W2020532704 cites W2010740532 @default.
• W2020532704 cites W2034280067 @default.
• W2020532704 cites W2053630217 @default.
• W2020532704 cites W2054263994 @default.
• W2020532704 cites W2064788529 @default.
• W2020532704 cites W2064848179 @default.
• W2020532704 cites W2065551702 @default.
• W2020532704 cites W2066668041 @default.
• W2020532704 cites W2081135713 @default.
• W2020532704 cites W2138270253 @default.
• W2020532704 cites W2167239451 @default.
• W2020532704 cites W2408912605 @default.
• W2020532704 cites W246524095 @default.
• W2020532704 doi "https://doi.org/10.1073/pnas.89.24.12053" @default.
• W2020532704 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/50696" @default.
• W2020532704 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1465439" @default.
• W2020532704 hasPublicationYear "1992" @default.
• W2020532704 type Work @default.
• W2020532704 sameAs 2020532704 @default.
• W2020532704 citedByCount "37" @default.
• W2020532704 countsByYear W20205327042016 @default.
• W2020532704 countsByYear W20205327042018 @default.
• W2020532704 countsByYear W20205327042019 @default.
• W2020532704 countsByYear W20205327042020 @default.
• W2020532704 countsByYear W20205327042021 @default.
• W2020532704 countsByYear W20205327042022 @default.
• W2020532704 crossrefType "journal-article" @default.
• W2020532704 hasAuthorship W2020532704A5016887845 @default.
• W2020532704 hasAuthorship W2020532704A5022318117 @default.
• W2020532704 hasAuthorship W2020532704A5027270763 @default.
• W2020532704 hasAuthorship W2020532704A5045786825 @default.
• W2020532704 hasAuthorship W2020532704A5088480931 @default.
• W2020532704 hasBestOaLocation W20205327042 @default.
• W2020532704 hasConcept C101762097 @default.
• W2020532704 hasConcept C104317684 @default.
• W2020532704 hasConcept C138885662 @default.
• W2020532704 hasConcept C150194340 @default.
• W2020532704 hasConcept C153911025 @default.
• W2020532704 hasConcept C179926584 @default.
• W2020532704 hasConcept C181199279 @default.
• W2020532704 hasConcept C194583182 @default.
• W2020532704 hasConcept C36823959 @default.
• W2020532704 hasConcept C41895202 @default.
• W2020532704 hasConcept C55493867 @default.
• W2020532704 hasConcept C58824617 @default.
• W2020532704 hasConcept C86803240 @default.
• W2020532704 hasConcept C95444343 @default.
• W2020532704 hasConceptScore W2020532704C101762097 @default.
• W2020532704 hasConceptScore W2020532704C104317684 @default.
• W2020532704 hasConceptScore W2020532704C138885662 @default.
• W2020532704 hasConceptScore W2020532704C150194340 @default.
• W2020532704 hasConceptScore W2020532704C153911025 @default.
• W2020532704 hasConceptScore W2020532704C179926584 @default.
• W2020532704 hasConceptScore W2020532704C181199279 @default.
• W2020532704 hasConceptScore W2020532704C194583182 @default.
• W2020532704 hasConceptScore W2020532704C36823959 @default.
• W2020532704 hasConceptScore W2020532704C41895202 @default.
• W2020532704 hasConceptScore W2020532704C55493867 @default.
• W2020532704 hasConceptScore W2020532704C58824617 @default.
• W2020532704 hasConceptScore W2020532704C86803240 @default.
• W2020532704 hasConceptScore W2020532704C95444343 @default.
• W2020532704 hasIssue "24" @default.
• W2020532704 hasLocation W20205327041 @default.
• W2020532704 hasLocation W20205327042 @default.
• W2020532704 hasLocation W20205327043 @default.
• W2020532704 hasLocation W20205327044 @default.
• W2020532704 hasOpenAccess W2020532704 @default.
• W2020532704 hasPrimaryLocation W20205327041 @default.
• W2020532704 hasRelatedWork W1567451703 @default.
• W2020532704 hasRelatedWork W1573549078 @default.
• W2020532704 hasRelatedWork W1977599835 @default.
• W2020532704 hasRelatedWork W1983118793 @default.
• W2020532704 hasRelatedWork W1988096767 @default.
• W2020532704 hasRelatedWork W2009966535 @default.
• W2020532704 hasRelatedWork W2080865520 @default.

• next