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• W2020551750 startingPage "553" @default.
• W2020551750 abstract "The aim of this study was to develop self emulsifying drug delivery systems (SEDDS) of glipizide and to convert it into solid SEDDS (S-SEDDS) using Syloid® 244 FP as adsorbent. Solubility study, ternary phase diagram, robustness to dilution, thermodynamic stability study and globule size analysis were adopted to optimize liquid SEDDS. S-SEDDS were evaluated for various studies including in vivo study. The optimized liquid SEDDS formulation consisted of phosphatidylcholine, Tween 80 and Transcutol P as oil, surfactant and cosolvent. In vivo study demonstrated that blood glucose levels were efficiently controlled with S-SEDDS compared with pure drug. The results of this study suggest the potential use of developed S-SEDDS formulation for the delivery of poorly water-soluble drug glipizide." @default.
• W2020551750 created "2016-06-24" @default.
• W2020551750 creator A5014679846 @default.
• W2020551750 creator A5014768599 @default.
• W2020551750 creator A5064058260 @default.
• W2020551750 date "2015-02-01" @default.
• W2020551750 modified "2023-10-16" @default.
• W2020551750 title "Self emulsifying drug delivery system for enhanced solubility and dissolution of glipizide" @default.
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• W2020551750 doi "https://doi.org/10.1016/j.colsurfb.2014.11.022" @default.
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