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- W2020631100 abstract "Sublytic concentrations of polyoxyethylene ether detergents are able to reduce the direct current (dc) resistance of lipid bilayer membranes. The order of cation effectiveness in lowering bilayer resistance is: K+ > Rb+ > Cs+ > Na+ = Li+. The decrease in bilayer resistance is transient when the detergent is present on one side of the film. The time required for maximum decrease in resistance is dependent on the concentration of detergent added. Multimolecular aggregates of Triton are involved in the resistance-lowering process. The data indicate that these aggregates interact with lipid in the bilayer. A mechanism is proposed by which lipid-Triton complexes enhance the permeability of bilayer membranes to cations, particularly to K+. The studies summarized in this communication and the accompanying manuscript suggest that detergents with a polyoxyethylene ether structure act as ionophores which are rather specific for K+." @default.
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- W2020631100 title "The interaction of nonionic detergents with lipid bilayer membranes" @default.
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- W2020631100 doi "https://doi.org/10.1016/0003-9861(72)90271-8" @default.
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