FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020656961> ?p ?o ?g. }

• W2020656961 endingPage "550" @default.
• W2020656961 startingPage "544" @default.
• W2020656961 abstract "Abstract Membranes were prepared from fresh, washed human erythrocytes by hemolysis and washing with 5 m m sodium phosphate buffer (pH 7.4). The mean residue ellipticity, [θ], of erythrocyte membrane circular dichroism was altered by prostaglandin E 1 or prostaglandin F 2α at 37 °C when observed from 250 nm to 190 nm. The decrease in negativity of [θ] with 10 −6 m prostaglandin E 1 was 12.7% at 222 nm and 17.7% at 208 nm, and with 10 −6 m prostaglandin F 2α 22.5% and 34.2%, respectively ( P −5 m to 3 × 10 −12 m was evident. A persistent alteration of [θ] with prostaglandin was observed at 37 °C. Transient change of [θ] occurred at 25 °C with prostaglandin. No change of [θ] was observed at 15 or 20 °C. Buffer or palmitic acid were without effect on membrane [θ]. Phosphatidyl inositol or methyl arachidonate caused an increase in negativity of membrane spectra. The observed alterations of membrane [θ] did not arise from changes in light scattering as the OD 700 –OD 200 of membranes was not changed by prostaglandin. Effects of prostaglandin were not dependent on light path length. The prostaglandin E 1 antagonist, 7-oxa-13-prostynoic acid, at 10 −7 m produced no change of [θ] of membrane spectra and prevented the otherwise demonstrable effects of 10 −10 m prostaglandin E 1 on [θ]. The decrease in negativity of [θ] at 222 nm is indicative of a decrease in ellipticity of membrane protein. These studies suggest that prostaglandins may act by inducing a conformational change in membrane protein." @default.
• W2020656961 created "2016-06-24" @default.
• W2020656961 creator A5016162050 @default.
• W2020656961 creator A5035899633 @default.
• W2020656961 date "1974-10-01" @default.
• W2020656961 modified "2023-10-16" @default.
• W2020656961 title "Conformational changes in erythrocyte membranes by prostaglandins as measured by circular dichroism" @default.
• W2020656961 cites W1514001920 @default.
• W2020656961 cites W1775749144 @default.
• W2020656961 cites W2003414760 @default.
• W2020656961 cites W2009572080 @default.
• W2020656961 cites W2020774182 @default.
• W2020656961 cites W2022182129 @default.
• W2020656961 cites W2026887728 @default.
• W2020656961 cites W2049819751 @default.
• W2020656961 cites W2052664734 @default.
• W2020656961 cites W2057634941 @default.
• W2020656961 cites W2064977930 @default.
• W2020656961 cites W2066537184 @default.
• W2020656961 cites W2082412305 @default.
• W2020656961 cites W2125384435 @default.
• W2020656961 doi "https://doi.org/10.1016/0003-9861(74)90065-4" @default.
• W2020656961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4477702" @default.
• W2020656961 hasPublicationYear "1974" @default.
• W2020656961 type Work @default.
• W2020656961 sameAs 2020656961 @default.
• W2020656961 citedByCount "20" @default.
• W2020656961 crossrefType "journal-article" @default.
• W2020656961 hasAuthorship W2020656961A5016162050 @default.
• W2020656961 hasAuthorship W2020656961A5035899633 @default.
• W2020656961 hasConcept C12554922 @default.
• W2020656961 hasConcept C133571119 @default.
• W2020656961 hasConcept C185592680 @default.
• W2020656961 hasConcept C2993443003 @default.
• W2020656961 hasConcept C41625074 @default.
• W2020656961 hasConcept C55493867 @default.
• W2020656961 hasConcept C8010536 @default.
• W2020656961 hasConcept C86803240 @default.
• W2020656961 hasConceptScore W2020656961C12554922 @default.
• W2020656961 hasConceptScore W2020656961C133571119 @default.
• W2020656961 hasConceptScore W2020656961C185592680 @default.
• W2020656961 hasConceptScore W2020656961C2993443003 @default.
• W2020656961 hasConceptScore W2020656961C41625074 @default.
• W2020656961 hasConceptScore W2020656961C55493867 @default.
• W2020656961 hasConceptScore W2020656961C8010536 @default.
• W2020656961 hasConceptScore W2020656961C86803240 @default.
• W2020656961 hasIssue "2" @default.
• W2020656961 hasLocation W20206569611 @default.
• W2020656961 hasLocation W20206569612 @default.
• W2020656961 hasOpenAccess W2020656961 @default.
• W2020656961 hasPrimaryLocation W20206569611 @default.
• W2020656961 hasRelatedWork W1964004398 @default.
• W2020656961 hasRelatedWork W1985287626 @default.
• W2020656961 hasRelatedWork W1993740563 @default.
• W2020656961 hasRelatedWork W2010766053 @default.
• W2020656961 hasRelatedWork W2032161274 @default.
• W2020656961 hasRelatedWork W2060469118 @default.
• W2020656961 hasRelatedWork W2072917526 @default.
• W2020656961 hasRelatedWork W2093666789 @default.
• W2020656961 hasRelatedWork W3110055093 @default.
• W2020656961 hasRelatedWork W3171224921 @default.
• W2020656961 hasVolume "164" @default.
• W2020656961 isParatext "false" @default.
• W2020656961 isRetracted "false" @default.
• W2020656961 magId "2020656961" @default.
• W2020656961 workType "article" @default.