FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020672863> ?p ?o ?g. }

• W2020672863 endingPage "e1000066" @default.
• W2020672863 startingPage "e1000066" @default.
• W2020672863 abstract "Mortality in HIV-infected patients who have access to highly active antiretroviral therapy (ART) has declined in sub-Saharan Africa, but it is unclear how mortality compares to the non-HIV-infected population. We compared mortality rates observed in HIV-1-infected patients starting ART with non-HIV-related background mortality in four countries in sub-Saharan Africa.Patients enrolled in antiretroviral treatment programmes in Côte d'Ivoire, Malawi, South Africa, and Zimbabwe were included. We calculated excess mortality rates and standardised mortality ratios (SMRs) with 95% confidence intervals (CIs). Expected numbers of deaths were obtained using estimates of age-, sex-, and country-specific, HIV-unrelated, mortality rates from the Global Burden of Disease project. Among 13,249 eligible patients 1,177 deaths were recorded during 14,695 person-years of follow-up. The median age was 34 y, 8,831 (67%) patients were female, and 10,811 of 12,720 patients (85%) with information on clinical stage had advanced disease when starting ART. The excess mortality rate was 17.5 (95% CI 14.5-21.1) per 100 person-years SMR in patients who started ART with a CD4 cell count of less than 25 cells/microl and World Health Organization (WHO) stage III/IV, compared to 1.00 (0.55-1.81) per 100 person-years in patients who started with 200 cells/microl or above with WHO stage I/II. The corresponding SMRs were 47.1 (39.1-56.6) and 3.44 (1.91-6.17). Among patients who started ART with 200 cells/microl or above in WHO stage I/II and survived the first year of ART, the excess mortality rate was 0.27 (0.08-0.94) per 100 person-years and the SMR was 1.14 (0.47-2.77).Mortality of HIV-infected patients treated with combination ART in sub-Saharan Africa continues to be higher than in the general population, but for some patients excess mortality is moderate and reaches that of the general population in the second year of ART. Much of the excess mortality might be prevented by timely initiation of ART." @default.
• W2020672863 created "2016-06-24" @default.
• W2020672863 creator A5003424194 @default.
• W2020672863 creator A5015915512 @default.
• W2020672863 creator A5017081649 @default.
• W2020672863 creator A5032374309 @default.
• W2020672863 creator A5049440373 @default.
• W2020672863 creator A5051693361 @default.
• W2020672863 creator A5074055717 @default.
• W2020672863 creator A5077161809 @default.
• W2020672863 creator A5086930822 @default.
• W2020672863 date "2009-04-28" @default.
• W2020672863 modified "2023-10-16" @default.
• W2020672863 title "Mortality of HIV-Infected Patients Starting Antiretroviral Therapy in Sub-Saharan Africa: Comparison with HIV-Unrelated Mortality" @default.
• W2020672863 cites W1225087940 @default.
• W2020672863 cites W1573558157 @default.
• W2020672863 cites W1593339216 @default.
• W2020672863 cites W1717206243 @default.
• W2020672863 cites W1983946306 @default.
• W2020672863 cites W1992237955 @default.
• W2020672863 cites W1999408007 @default.
• W2020672863 cites W2017793579 @default.
• W2020672863 cites W2020705331 @default.
• W2020672863 cites W2030978808 @default.
• W2020672863 cites W2038647399 @default.
• W2020672863 cites W2054931962 @default.
• W2020672863 cites W2056440737 @default.
• W2020672863 cites W2061577516 @default.
• W2020672863 cites W2064183913 @default.
• W2020672863 cites W2068392998 @default.
• W2020672863 cites W2071839943 @default.
• W2020672863 cites W2077124024 @default.
• W2020672863 cites W2091582739 @default.
• W2020672863 cites W2099048056 @default.
• W2020672863 cites W2111259846 @default.
• W2020672863 cites W2115830594 @default.
• W2020672863 cites W2118502261 @default.
• W2020672863 cites W2118896333 @default.
• W2020672863 cites W2120646318 @default.
• W2020672863 cites W2124801504 @default.
• W2020672863 cites W2139894829 @default.
• W2020672863 cites W2141332234 @default.
• W2020672863 cites W2147416239 @default.
• W2020672863 cites W2155527293 @default.
• W2020672863 cites W2157981460 @default.
• W2020672863 cites W2160888326 @default.
• W2020672863 cites W2171960881 @default.
• W2020672863 cites W2187955543 @default.
• W2020672863 cites W2329917131 @default.
• W2020672863 cites W2480680997 @default.
• W2020672863 cites W4292672078 @default.
• W2020672863 doi "https://doi.org/10.1371/journal.pmed.1000066" @default.
• W2020672863 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2667633" @default.
• W2020672863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19399157" @default.
• W2020672863 hasPublicationYear "2009" @default.
• W2020672863 type Work @default.
• W2020672863 sameAs 2020672863 @default.
• W2020672863 citedByCount "172" @default.
• W2020672863 countsByYear W20206728632012 @default.
• W2020672863 countsByYear W20206728632013 @default.
• W2020672863 countsByYear W20206728632014 @default.
• W2020672863 countsByYear W20206728632015 @default.
• W2020672863 countsByYear W20206728632016 @default.
• W2020672863 countsByYear W20206728632017 @default.
• W2020672863 countsByYear W20206728632018 @default.
• W2020672863 countsByYear W20206728632019 @default.
• W2020672863 countsByYear W20206728632020 @default.
• W2020672863 countsByYear W20206728632021 @default.
• W2020672863 countsByYear W20206728632022 @default.
• W2020672863 countsByYear W20206728632023 @default.
• W2020672863 crossrefType "journal-article" @default.
• W2020672863 hasAuthorship W2020672863A5003424194 @default.
• W2020672863 hasAuthorship W2020672863A5015915512 @default.
• W2020672863 hasAuthorship W2020672863A5017081649 @default.
• W2020672863 hasAuthorship W2020672863A5032374309 @default.
• W2020672863 hasAuthorship W2020672863A5049440373 @default.
• W2020672863 hasAuthorship W2020672863A5051693361 @default.
• W2020672863 hasAuthorship W2020672863A5074055717 @default.
• W2020672863 hasAuthorship W2020672863A5077161809 @default.
• W2020672863 hasAuthorship W2020672863A5086930822 @default.
• W2020672863 hasBestOaLocation W20206728631 @default.
• W2020672863 hasConcept C126322002 @default.
• W2020672863 hasConcept C142462285 @default.
• W2020672863 hasConcept C144024400 @default.
• W2020672863 hasConcept C149923435 @default.
• W2020672863 hasConcept C179755657 @default.
• W2020672863 hasConcept C187212893 @default.
• W2020672863 hasConcept C203014093 @default.
• W2020672863 hasConcept C2908647359 @default.
• W2020672863 hasConcept C2993143319 @default.
• W2020672863 hasConcept C3013748606 @default.
• W2020672863 hasConcept C44249647 @default.
• W2020672863 hasConcept C71924100 @default.
• W2020672863 hasConcept C99454951 @default.
• W2020672863 hasConceptScore W2020672863C126322002 @default.
• W2020672863 hasConceptScore W2020672863C142462285 @default.
• W2020672863 hasConceptScore W2020672863C144024400 @default.
• W2020672863 hasConceptScore W2020672863C149923435 @default.

• next