FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020679328> ?p ?o ?g. }

• W2020679328 endingPage "8306" @default.
• W2020679328 startingPage "8300" @default.
• W2020679328 abstract "The BCL-2 gene encodes a 25 kDa membrane protein that plays critical roles in the control of apoptosis. The regulation of BCL-2 gene expression is highly complex and occurs both transcriptionally and posttranscriptionally. In particular, the 5' upstream region of BCL-2 contains a number of elements that control its expression. We have identified a highly conserved 25-nucleotide G-rich sequence (BCL2Q), with potential to fold into a RNA G-quadruplex structure, located 42 nucleotides upstream of the translation start site of human BCL-2. In this study, we used a series of biophysical experiments to show that the BCL2Q sequence folds into a stable RNA G-quadruplex in vitro, and we conducted functional luciferase reporter-based assays, in a cell-free lysate and in three types of human cell lines, to demonstrate that the BCL2Q sequence modulates protein expression in the context of the 493-nucleotide native 5' untranslated region of BCL-2." @default.
• W2020679328 created "2016-06-24" @default.
• W2020679328 creator A5007212140 @default.
• W2020679328 creator A5040551102 @default.
• W2020679328 creator A5085902446 @default.
• W2020679328 date "2010-09-01" @default.
• W2020679328 modified "2023-10-16" @default.
• W2020679328 title "The <i>BCL-2</i> 5′ Untranslated Region Contains an RNA G-Quadruplex-Forming Motif That Modulates Protein Expression" @default.
• W2020679328 cites W1568678893 @default.
• W2020679328 cites W1966380992 @default.
• W2020679328 cites W1967354499 @default.
• W2020679328 cites W1967798131 @default.
• W2020679328 cites W1971025296 @default.
• W2020679328 cites W1972311492 @default.
• W2020679328 cites W1974175020 @default.
• W2020679328 cites W1980891354 @default.
• W2020679328 cites W1991950561 @default.
• W2020679328 cites W1993726540 @default.
• W2020679328 cites W1993738860 @default.
• W2020679328 cites W1994435087 @default.
• W2020679328 cites W199455914 @default.
• W2020679328 cites W2007057690 @default.
• W2020679328 cites W2008898220 @default.
• W2020679328 cites W2009183764 @default.
• W2020679328 cites W2014161729 @default.
• W2020679328 cites W2017844053 @default.
• W2020679328 cites W2024582476 @default.
• W2020679328 cites W2027738669 @default.
• W2020679328 cites W2031428346 @default.
• W2020679328 cites W2032698727 @default.
• W2020679328 cites W2034558506 @default.
• W2020679328 cites W2040945511 @default.
• W2020679328 cites W2043550667 @default.
• W2020679328 cites W2044279725 @default.
• W2020679328 cites W2054584424 @default.
• W2020679328 cites W2058920315 @default.
• W2020679328 cites W2064109910 @default.
• W2020679328 cites W2066055007 @default.
• W2020679328 cites W2068994981 @default.
• W2020679328 cites W2075309417 @default.
• W2020679328 cites W2079768304 @default.
• W2020679328 cites W2085140901 @default.
• W2020679328 cites W2108244474 @default.
• W2020679328 cites W2115268409 @default.
• W2020679328 cites W2122095304 @default.
• W2020679328 cites W2122141896 @default.
• W2020679328 cites W2122467851 @default.
• W2020679328 cites W2124166350 @default.
• W2020679328 cites W2124419343 @default.
• W2020679328 cites W2130652515 @default.
• W2020679328 cites W2133397461 @default.
• W2020679328 cites W2151639461 @default.
• W2020679328 cites W2168146598 @default.
• W2020679328 cites W2407977596 @default.
• W2020679328 cites W302399912 @default.
• W2020679328 cites W89280349 @default.
• W2020679328 doi "https://doi.org/10.1021/bi100957h" @default.
• W2020679328 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3038430" @default.
• W2020679328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20726580" @default.
• W2020679328 hasPublicationYear "2010" @default.
• W2020679328 type Work @default.
• W2020679328 sameAs 2020679328 @default.
• W2020679328 citedByCount "131" @default.
• W2020679328 countsByYear W20206793282012 @default.
• W2020679328 countsByYear W20206793282013 @default.
• W2020679328 countsByYear W20206793282014 @default.
• W2020679328 countsByYear W20206793282015 @default.
• W2020679328 countsByYear W20206793282016 @default.
• W2020679328 countsByYear W20206793282017 @default.
• W2020679328 countsByYear W20206793282018 @default.
• W2020679328 countsByYear W20206793282019 @default.
• W2020679328 countsByYear W20206793282020 @default.
• W2020679328 countsByYear W20206793282021 @default.
• W2020679328 countsByYear W20206793282022 @default.
• W2020679328 countsByYear W20206793282023 @default.
• W2020679328 crossrefType "journal-article" @default.
• W2020679328 hasAuthorship W2020679328A5007212140 @default.
• W2020679328 hasAuthorship W2020679328A5040551102 @default.
• W2020679328 hasAuthorship W2020679328A5085902446 @default.
• W2020679328 hasBestOaLocation W20206793282 @default.
• W2020679328 hasConcept C104317684 @default.
• W2020679328 hasConcept C105580179 @default.
• W2020679328 hasConcept C114847915 @default.
• W2020679328 hasConcept C149364088 @default.
• W2020679328 hasConcept C150194340 @default.
• W2020679328 hasConcept C153911025 @default.
• W2020679328 hasConcept C22667442 @default.
• W2020679328 hasConcept C54355233 @default.
• W2020679328 hasConcept C67705224 @default.
• W2020679328 hasConcept C86803240 @default.
• W2020679328 hasConcept C89604277 @default.
• W2020679328 hasConcept C95444343 @default.
• W2020679328 hasConceptScore W2020679328C104317684 @default.
• W2020679328 hasConceptScore W2020679328C105580179 @default.
• W2020679328 hasConceptScore W2020679328C114847915 @default.
• W2020679328 hasConceptScore W2020679328C149364088 @default.
• W2020679328 hasConceptScore W2020679328C150194340 @default.
• W2020679328 hasConceptScore W2020679328C153911025 @default.

• next