FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020697265> ?p ?o ?g. }

• W2020697265 endingPage "222" @default.
• W2020697265 startingPage "215" @default.
• W2020697265 abstract "The complex of L-L-boronophenylalanine (L-p-BPA) with fructose has been used for the past 5 years in clinical trials of boron neutron capture therapy to treat both melanoma and glioblastoma multiforme. However, the structure of this complex in water buffered at physiologic pH has not been established. In the (1)H NMR spectra (D(2)O buffered at pD 7.4) of the complex of L-p-BPA with various carbohydrates, the upfield chemical shifts of the aromatic protons of L-p-BPA confirm that the boron atom is negatively charged and tetrahedral. In the (13)C NMR spectrum of the complex of L-p-BPA with U-(13)C labeled fructose, the chemical shifts and (1)J(CC) coupling constants are consistent with fructose adopting the beta-D-fructofuranose form. In addition, the (1)J(CC) coupling constants along with the binding constants measured for L-p-BPA with a series of monosaccharides and disaccharides seem to suggest that the beta-D-fructofuranose 2,3,6-(p-phenylalanylorthoboronate) structure strongly predominates, with free L-p-BPA and fructose the only other species detected." @default.
• W2020697265 created "2016-06-24" @default.
• W2020697265 creator A5020007927 @default.
• W2020697265 creator A5064094467 @default.
• W2020697265 creator A5078688472 @default.
• W2020697265 creator A5080142953 @default.
• W2020697265 creator A5084756016 @default.
• W2020697265 creator A5086723077 @default.
• W2020697265 date "2000-02-01" @default.
• W2020697265 modified "2023-09-23" @default.
• W2020697265 title "Studies on the Structure of the Complex of the Boron Neutron Capture Therapy Drug, L‐p‐Boronophenylalanine, with Fructose and Related Carbohydrates: Chemical and 13C NMR evidence for the β‐D‐Fructofuranose 2,3,6‐(p‐Phenylalanylorthoboronate) Structure" @default.
• W2020697265 cites W1964292815 @default.
• W2020697265 cites W1982390919 @default.
• W2020697265 cites W1987162978 @default.
• W2020697265 cites W1991527689 @default.
• W2020697265 cites W1992738865 @default.
• W2020697265 cites W1994545680 @default.
• W2020697265 cites W1995383317 @default.
• W2020697265 cites W2003942692 @default.
• W2020697265 cites W2004647313 @default.
• W2020697265 cites W2004823560 @default.
• W2020697265 cites W2004840733 @default.
• W2020697265 cites W2007074029 @default.
• W2020697265 cites W2021091113 @default.
• W2020697265 cites W2021552092 @default.
• W2020697265 cites W2026858635 @default.
• W2020697265 cites W2031906526 @default.
• W2020697265 cites W2043740466 @default.
• W2020697265 cites W2052038618 @default.
• W2020697265 cites W2059589933 @default.
• W2020697265 cites W2071522699 @default.
• W2020697265 cites W2079178782 @default.
• W2020697265 cites W2085731391 @default.
• W2020697265 cites W2133286329 @default.
• W2020697265 cites W2149962250 @default.
• W2020697265 cites W2151051629 @default.
• W2020697265 cites W2152649528 @default.
• W2020697265 cites W2313658489 @default.
• W2020697265 cites W2334892113 @default.
• W2020697265 cites W239834479 @default.
• W2020697265 cites W2409047160 @default.
• W2020697265 cites W241063502 @default.
• W2020697265 cites W2951345653 @default.
• W2020697265 cites W3022068974 @default.
• W2020697265 doi "https://doi.org/10.1002/(sici)1520-6017(200002)89:2<215::aid-jps8>3.0.co;2-p" @default.
• W2020697265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10688750" @default.
• W2020697265 hasPublicationYear "2000" @default.
• W2020697265 type Work @default.
• W2020697265 sameAs 2020697265 @default.
• W2020697265 citedByCount "31" @default.
• W2020697265 countsByYear W20206972652012 @default.
• W2020697265 countsByYear W20206972652013 @default.
• W2020697265 countsByYear W20206972652015 @default.
• W2020697265 countsByYear W20206972652019 @default.
• W2020697265 countsByYear W20206972652021 @default.
• W2020697265 countsByYear W20206972652022 @default.
• W2020697265 crossrefType "journal-article" @default.
• W2020697265 hasAuthorship W2020697265A5020007927 @default.
• W2020697265 hasAuthorship W2020697265A5064094467 @default.
• W2020697265 hasAuthorship W2020697265A5078688472 @default.
• W2020697265 hasAuthorship W2020697265A5080142953 @default.
• W2020697265 hasAuthorship W2020697265A5084756016 @default.
• W2020697265 hasAuthorship W2020697265A5086723077 @default.
• W2020697265 hasConcept C103319777 @default.
• W2020697265 hasConcept C111429119 @default.
• W2020697265 hasConcept C118859902 @default.
• W2020697265 hasConcept C121332964 @default.
• W2020697265 hasConcept C147789679 @default.
• W2020697265 hasConcept C163111631 @default.
• W2020697265 hasConcept C178790620 @default.
• W2020697265 hasConcept C185592680 @default.
• W2020697265 hasConcept C2776970464 @default.
• W2020697265 hasConcept C46141821 @default.
• W2020697265 hasConcept C501308230 @default.
• W2020697265 hasConcept C66974803 @default.
• W2020697265 hasConcept C71240020 @default.
• W2020697265 hasConcept C8010536 @default.
• W2020697265 hasConceptScore W2020697265C103319777 @default.
• W2020697265 hasConceptScore W2020697265C111429119 @default.
• W2020697265 hasConceptScore W2020697265C118859902 @default.
• W2020697265 hasConceptScore W2020697265C121332964 @default.
• W2020697265 hasConceptScore W2020697265C147789679 @default.
• W2020697265 hasConceptScore W2020697265C163111631 @default.
• W2020697265 hasConceptScore W2020697265C178790620 @default.
• W2020697265 hasConceptScore W2020697265C185592680 @default.
• W2020697265 hasConceptScore W2020697265C2776970464 @default.
• W2020697265 hasConceptScore W2020697265C46141821 @default.
• W2020697265 hasConceptScore W2020697265C501308230 @default.
• W2020697265 hasConceptScore W2020697265C66974803 @default.
• W2020697265 hasConceptScore W2020697265C71240020 @default.
• W2020697265 hasConceptScore W2020697265C8010536 @default.
• W2020697265 hasIssue "2" @default.
• W2020697265 hasLocation W20206972651 @default.
• W2020697265 hasLocation W20206972652 @default.
• W2020697265 hasOpenAccess W2020697265 @default.
• W2020697265 hasPrimaryLocation W20206972651 @default.
• W2020697265 hasRelatedWork W1541753903 @default.
• W2020697265 hasRelatedWork W1971980089 @default.

• next