FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020698441> ?p ?o ?g. }

• W2020698441 endingPage "100" @default.
• W2020698441 startingPage "97" @default.
• W2020698441 abstract "Transplantation of the liver results in surgical denervation of the organ. However, it is not known whether and to what extent sympathetic reinnervation occurs postoperatively in the transplanted human liver. Thirty-two liver biopsies (right lobe) were obtained from 13 liver-transplanted patients 1, 3, 6, 12 or 30 months after transplantation and 11 biopsies were obtained from 11 non-transplanted subjects with normal liver tests. The concentrations of the sympathetic neurotransmitter norepinephrine and of epinephrine were determined in liver tissue homogenates. The concentration of norepinephrine was 0.019±0.05 nmol·g wet liver tissue−1 (mean and SE, n=32) in the transplanted patients, which was only 1% of the concentration in biopsies from control subjects (2.180±0.420 nmol·g wet liver tissue−1). The hepatic norepinephrine concentration did not increase significantly over time in liver-transplanted patients during the observation period (0.015±0.008 nmol·g wet wt−1 (1 month post) (n=8) vs. 0.024±0.018 nmol·g wet wt−1 (12 months post) (n=6) and 0.012±0.006 nmol·g wet wt−1 (30 months post) (n=5)) (p<0.05). The liver tissue concentration of epinephrine was markedly lower in liver-transplanted subjects (0.01±0.003 nmol·g wet tissue−1) than in control subjects (0.04±0.007 nmol·g−1) (p<0.01). This study indicates that within the first years after transplantation, there is no evidence of sympathetic liver nerve reinnervation in liver-transplanted patients. Transplantation of the liver results in surgical denervation of the organ. However, it is not known whether and to what extent sympathetic reinnervation occurs postoperatively in the transplanted human liver. Thirty-two liver biopsies (right lobe) were obtained from 13 liver-transplanted patients 1, 3, 6, 12 or 30 months after transplantation and 11 biopsies were obtained from 11 non-transplanted subjects with normal liver tests. The concentrations of the sympathetic neurotransmitter norepinephrine and of epinephrine were determined in liver tissue homogenates. The concentration of norepinephrine was 0.019±0.05 nmol·g wet liver tissue−1 (mean and SE, n=32) in the transplanted patients, which was only 1% of the concentration in biopsies from control subjects (2.180±0.420 nmol·g wet liver tissue−1). The hepatic norepinephrine concentration did not increase significantly over time in liver-transplanted patients during the observation period (0.015±0.008 nmol·g wet wt−1 (1 month post) (n=8) vs. 0.024±0.018 nmol·g wet wt−1 (12 months post) (n=6) and 0.012±0.006 nmol·g wet wt−1 (30 months post) (n=5)) (p<0.05). The liver tissue concentration of epinephrine was markedly lower in liver-transplanted subjects (0.01±0.003 nmol·g wet tissue−1) than in control subjects (0.04±0.007 nmol·g−1) (p<0.01). This study indicates that within the first years after transplantation, there is no evidence of sympathetic liver nerve reinnervation in liver-transplanted patients." @default.
• W2020698441 created "2016-06-24" @default.
• W2020698441 creator A5009840519 @default.
• W2020698441 creator A5020304519 @default.
• W2020698441 creator A5055869865 @default.
• W2020698441 creator A5058618509 @default.
• W2020698441 creator A5067335445 @default.
• W2020698441 creator A5073204478 @default.
• W2020698441 date "1994-01-01" @default.
• W2020698441 modified "2023-10-18" @default.
• W2020698441 title "No reinnervation of hepatic sympathetic nerves after liver transplantation in human subjects" @default.
• W2020698441 cites W1980981311 @default.
• W2020698441 cites W1981056109 @default.
• W2020698441 cites W1984619996 @default.
• W2020698441 cites W1986719639 @default.
• W2020698441 cites W1989619973 @default.
• W2020698441 cites W1991747485 @default.
• W2020698441 cites W2025117833 @default.
• W2020698441 cites W2047161211 @default.
• W2020698441 cites W2070297934 @default.
• W2020698441 cites W2071732771 @default.
• W2020698441 cites W2157358406 @default.
• W2020698441 cites W2273980639 @default.
• W2020698441 cites W2438204802 @default.
• W2020698441 cites W2472881723 @default.
• W2020698441 doi "https://doi.org/10.1016/s0168-8278(05)80473-8" @default.
• W2020698441 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8201229" @default.
• W2020698441 hasPublicationYear "1994" @default.
• W2020698441 type Work @default.
• W2020698441 sameAs 2020698441 @default.
• W2020698441 citedByCount "55" @default.
• W2020698441 countsByYear W20206984412012 @default.
• W2020698441 countsByYear W20206984412013 @default.
• W2020698441 countsByYear W20206984412014 @default.
• W2020698441 countsByYear W20206984412015 @default.
• W2020698441 countsByYear W20206984412016 @default.
• W2020698441 countsByYear W20206984412017 @default.
• W2020698441 countsByYear W20206984412019 @default.
• W2020698441 countsByYear W20206984412020 @default.
• W2020698441 countsByYear W20206984412021 @default.
• W2020698441 countsByYear W20206984412022 @default.
• W2020698441 crossrefType "journal-article" @default.
• W2020698441 hasAuthorship W2020698441A5009840519 @default.
• W2020698441 hasAuthorship W2020698441A5020304519 @default.
• W2020698441 hasAuthorship W2020698441A5055869865 @default.
• W2020698441 hasAuthorship W2020698441A5058618509 @default.
• W2020698441 hasAuthorship W2020698441A5067335445 @default.
• W2020698441 hasAuthorship W2020698441A5073204478 @default.
• W2020698441 hasConcept C126322002 @default.
• W2020698441 hasConcept C134018914 @default.
• W2020698441 hasConcept C141071460 @default.
• W2020698441 hasConcept C2775859304 @default.
• W2020698441 hasConcept C2776805190 @default.
• W2020698441 hasConcept C2778514916 @default.
• W2020698441 hasConcept C2779609443 @default.
• W2020698441 hasConcept C2779649809 @default.
• W2020698441 hasConcept C2909070644 @default.
• W2020698441 hasConcept C2911091166 @default.
• W2020698441 hasConcept C2992176824 @default.
• W2020698441 hasConcept C513476851 @default.
• W2020698441 hasConcept C71924100 @default.
• W2020698441 hasConceptScore W2020698441C126322002 @default.
• W2020698441 hasConceptScore W2020698441C134018914 @default.
• W2020698441 hasConceptScore W2020698441C141071460 @default.
• W2020698441 hasConceptScore W2020698441C2775859304 @default.
• W2020698441 hasConceptScore W2020698441C2776805190 @default.
• W2020698441 hasConceptScore W2020698441C2778514916 @default.
• W2020698441 hasConceptScore W2020698441C2779609443 @default.
• W2020698441 hasConceptScore W2020698441C2779649809 @default.
• W2020698441 hasConceptScore W2020698441C2909070644 @default.
• W2020698441 hasConceptScore W2020698441C2911091166 @default.
• W2020698441 hasConceptScore W2020698441C2992176824 @default.
• W2020698441 hasConceptScore W2020698441C513476851 @default.
• W2020698441 hasConceptScore W2020698441C71924100 @default.
• W2020698441 hasIssue "1" @default.
• W2020698441 hasLocation W20206984411 @default.
• W2020698441 hasLocation W20206984412 @default.
• W2020698441 hasOpenAccess W2020698441 @default.
• W2020698441 hasPrimaryLocation W20206984411 @default.
• W2020698441 hasRelatedWork W2017660431 @default.
• W2020698441 hasRelatedWork W2019625812 @default.
• W2020698441 hasRelatedWork W2031497790 @default.
• W2020698441 hasRelatedWork W2039599501 @default.
• W2020698441 hasRelatedWork W2065705452 @default.
• W2020698441 hasRelatedWork W21229474 @default.
• W2020698441 hasRelatedWork W2154059912 @default.
• W2020698441 hasRelatedWork W2789527358 @default.
• W2020698441 hasRelatedWork W4213431989 @default.
• W2020698441 hasRelatedWork W334575885 @default.
• W2020698441 hasVolume "20" @default.
• W2020698441 isParatext "false" @default.
• W2020698441 isRetracted "false" @default.
• W2020698441 magId "2020698441" @default.
• W2020698441 workType "article" @default.