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• W2020704865 abstract "A novel multiplexed sensing scheme based on the measurement of the magnetic susceptibility of the affinity captured target molecules on magnetic nanoparticles in liquid suspension is proposed. The AC magnetic susceptibility provides a measurement of Brownian relaxation behavior of biomolecules bound to magnetic nanoparticles (MNPs) that is related to its hydrodynamic size. A room temperature, compact AC susceptometer is designed and developed to measure complex AC magnetic susceptibility of such magnetic nanoparticles. The AC susceptometer exhibits high sensitivity in magnetic fields as low as 10 µT for 1 mg ml(-1) concentration and 5 µl volume, and is fully software programmable. The capability of biological sensing using the proposed scheme has been demonstrated in proof of principle using the binding of biotinylated horseradish peroxidase (HRP) to streptavidin-coated MNPs. The proposed technique and instrument are readily compatible with lab-on-chip applications for point-of-care medical applications." @default.
• W2020704865 created "2016-06-24" @default.
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• W2020704865 date "2011-01-17" @default.
• W2020704865 modified "2023-09-23" @default.
• W2020704865 title "Multiplexed sensing based on Brownian relaxation of magnetic nanoparticles using a compact AC susceptometer" @default.
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• W2020704865 doi "https://doi.org/10.1088/0957-4484/22/8/085501" @default.
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• W2020704865 hasPublicationYear "2011" @default.
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