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- W2020706532 abstract "Conflicts of interest: none declared. Sir, We report a further example of thalidomide provoking an exacerbation of psoriasis. A 41‐year‐old woman developed recurrent oral ulcers and itchy skin blisters of the upper and lower limbs (Fig. 1a), considered to be erythema multiforme histologically (Fig. 1b). Her autoimmune profile was normal. Her blisters were not well controlled by dapsone 150 mg daily over 2 years. She also had a long history of psoriasis with occasional outbreaks of guttate lesions. Thalidomide 100 mg daily was introduced and effectively controlled the erythema multiforme. The psoriasis flared 2 weeks after starting thalidomide, with plaque psoriasis on the dorsal surface of her hands, arms, scalp, back and lower limbs. As it was considered that thalidomide may have contributed to the psoriasis deterioration, the thalidomide was stopped. Calcipotriol ointment and betamethasone valerate were prescribed to control the psoriasis. Her plaque psoriasis settled quickly after 2 weeks of topical treatment." @default.
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- W2020706532 date "2006-02-20" @default.
- W2020706532 modified "2023-09-25" @default.
- W2020706532 title "Exacerbation of psoriasis by thalidomide in a patient with erythema multiforme" @default.
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- W2020706532 doi "https://doi.org/10.1111/j.1365-2133.2006.07149.x" @default.
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