FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020714280> ?p ?o ?g. }

• W2020714280 endingPage "2786" @default.
• W2020714280 startingPage "2778" @default.
• W2020714280 abstract "The incidence of lupus-like reactions (LLRs) in patients with inflammatory bowel disease (IBD) treated with anti-tumor necrosis factor (ATNF) has not been well defined. We aimed to characterize the features and predictors associated with LLR. We studied a cohort of adult patients with IBD treated with ATNF by a single specialist during 2009. Patients with LLR were characterized and compared with those without LLR for possible predictors. Twenty of 289 patients (6.9%) had LLR (19.9 cases per 1000 patient-years). Female gender and IBD-unclassified were more prevalent in the LLR group (85% versus 54%, P = 0.009; and 15% versus 2.2%, P = 0.018, respectively), with a hazard ratio of 3.89 (95% confidence interval = 1.12–13.55; P = 0.033) and 7.38 (95% confidence interval = 1.93–28.23; P = 0.003), respectively. ATNF duration was shorter in the LLR group (median, 1 year [interquartile range, 0–3] versus 3 years [interquartile range, 1–6.5], P = 0.005). Arthropathy was universal, followed by fatigue and dermatitis (30% each). Antinuclear antibodies were universally positive, and 16 of 20 had anti–double-stranded DNA. ATNF was discontinued in all; 8 patients required corticosteroids and 1 required hydroxychloroquine followed by complete clinical resolution (mean 7.9 ± 5.9 months). Antinuclear antibodies reverted or normalized in 7 of 16 patients (44%). Fourteen patients (70%) were switched to a second ATNF, 2 with concomitant immunomodulators, and 12 as monotherapy. One patient on ATNF monotherapy developed a second LLR and was successfully switched to a third ATNF. LLRs secondary to ATNFs are more frequent than previously reported, more common in women and IBD-unclassified. It is reversible with cessation of the culprit agent and steroids. Switching to an alternative ATNF rarely results in recurrence." @default.
• W2020714280 created "2016-06-24" @default.
• W2020714280 creator A5013079328 @default.
• W2020714280 creator A5022818325 @default.
• W2020714280 creator A5023182644 @default.
• W2020714280 creator A5044577178 @default.
• W2020714280 creator A5069738170 @default.
• W2020714280 creator A5091470733 @default.
• W2020714280 date "2013-12-01" @default.
• W2020714280 modified "2023-10-17" @default.
• W2020714280 title "The Incidence and Predictors of Lupus-like Reaction in Patients with IBD Treated with Anti-TNF Therapies" @default.
• W2020714280 cites W1504807220 @default.
• W2020714280 cites W1518420099 @default.
• W2020714280 cites W1971261585 @default.
• W2020714280 cites W1976546496 @default.
• W2020714280 cites W1978593886 @default.
• W2020714280 cites W1980464290 @default.
• W2020714280 cites W1983943495 @default.
• W2020714280 cites W1991810959 @default.
• W2020714280 cites W2004608617 @default.
• W2020714280 cites W2013361256 @default.
• W2020714280 cites W2018933969 @default.
• W2020714280 cites W2026116536 @default.
• W2020714280 cites W2029993898 @default.
• W2020714280 cites W2035129862 @default.
• W2020714280 cites W2063862099 @default.
• W2020714280 cites W2067477281 @default.
• W2020714280 cites W2068012094 @default.
• W2020714280 cites W2081229376 @default.
• W2020714280 cites W2094464340 @default.
• W2020714280 cites W2104125890 @default.
• W2020714280 cites W2104539207 @default.
• W2020714280 cites W2105311242 @default.
• W2020714280 cites W2105833786 @default.
• W2020714280 cites W2105968451 @default.
• W2020714280 cites W2111570058 @default.
• W2020714280 cites W2121609590 @default.
• W2020714280 cites W2126510103 @default.
• W2020714280 cites W2127693350 @default.
• W2020714280 cites W2131988977 @default.
• W2020714280 cites W2135423184 @default.
• W2020714280 cites W2137775651 @default.
• W2020714280 cites W2144550346 @default.
• W2020714280 cites W2152026434 @default.
• W2020714280 cites W2156250460 @default.
• W2020714280 cites W2166360124 @default.
• W2020714280 cites W2167404036 @default.
• W2020714280 cites W2168370388 @default.
• W2020714280 cites W2171122944 @default.
• W2020714280 cites W2171341132 @default.
• W2020714280 cites W2194019614 @default.
• W2020714280 cites W4239125410 @default.
• W2020714280 doi "https://doi.org/10.1097/01.mib.0000435435.91988.b6" @default.
• W2020714280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24185311" @default.
• W2020714280 hasPublicationYear "2013" @default.
• W2020714280 type Work @default.
• W2020714280 sameAs 2020714280 @default.
• W2020714280 citedByCount "21" @default.
• W2020714280 countsByYear W20207142802014 @default.
• W2020714280 countsByYear W20207142802015 @default.
• W2020714280 countsByYear W20207142802016 @default.
• W2020714280 countsByYear W20207142802017 @default.
• W2020714280 countsByYear W20207142802019 @default.
• W2020714280 countsByYear W20207142802020 @default.
• W2020714280 countsByYear W20207142802021 @default.
• W2020714280 countsByYear W20207142802022 @default.
• W2020714280 crossrefType "journal-article" @default.
• W2020714280 hasAuthorship W2020714280A5013079328 @default.
• W2020714280 hasAuthorship W2020714280A5022818325 @default.
• W2020714280 hasAuthorship W2020714280A5023182644 @default.
• W2020714280 hasAuthorship W2020714280A5044577178 @default.
• W2020714280 hasAuthorship W2020714280A5069738170 @default.
• W2020714280 hasAuthorship W2020714280A5091470733 @default.
• W2020714280 hasBestOaLocation W20207142801 @default.
• W2020714280 hasConcept C119060515 @default.
• W2020714280 hasConcept C120665830 @default.
• W2020714280 hasConcept C121332964 @default.
• W2020714280 hasConcept C126322002 @default.
• W2020714280 hasConcept C207103383 @default.
• W2020714280 hasConcept C2777138892 @default.
• W2020714280 hasConcept C2777575956 @default.
• W2020714280 hasConcept C2779134260 @default.
• W2020714280 hasConcept C2779384505 @default.
• W2020714280 hasConcept C2780132546 @default.
• W2020714280 hasConcept C44249647 @default.
• W2020714280 hasConcept C61511704 @default.
• W2020714280 hasConcept C71924100 @default.
• W2020714280 hasConcept C90924648 @default.
• W2020714280 hasConceptScore W2020714280C119060515 @default.
• W2020714280 hasConceptScore W2020714280C120665830 @default.
• W2020714280 hasConceptScore W2020714280C121332964 @default.
• W2020714280 hasConceptScore W2020714280C126322002 @default.
• W2020714280 hasConceptScore W2020714280C207103383 @default.
• W2020714280 hasConceptScore W2020714280C2777138892 @default.
• W2020714280 hasConceptScore W2020714280C2777575956 @default.
• W2020714280 hasConceptScore W2020714280C2779134260 @default.
• W2020714280 hasConceptScore W2020714280C2779384505 @default.
• W2020714280 hasConceptScore W2020714280C2780132546 @default.

• next