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- W2020751641 abstract "Ten saponins isolated from the leaves of Maesa lanceolata were tested for their antiviral, haemolytic and molluscicidal activities. The influence of the substitution pattern of these acylated triterpenoid saponins on their biological activities was investigated and structure-activity relationships were established. Maesasaponin VI(2) (3 beta-O-[[alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-galactopyranosyl-(1 --> 3)]-[beta-D-galactopyranosyl-(1 --> 2)]-beta-D-glucopyranuronyl]-21 beta,22 alpha-diangeloyloxy-13 beta,28-epoxyolean-16 alpha,28 alpha-diol), the most potent molluscicidal compound (LC(50) 0.5 ppm), also showed virucidal and haemolytic activity. In general, 21,22-diacylation appeared to be associated with a virucidal (reduction factor of the viral titer > or = 10(3) at 50 microg/ml) and haemolytic activity (HC(50) < or = 1 microg/ml)." @default.
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- W2020751641 date "2001-08-17" @default.
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- W2020751641 title "Antiviral, Haemolytic and Molluscicidal Activities of Triterpenoid Saponins from <i>Maesa lanceolata:</i> Establishment of Structure-Activity Relationships" @default.
- W2020751641 doi "https://doi.org/10.1055/s-2001-16489" @default.
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