FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020771285> ?p ?o ?g. }

• W2020771285 endingPage "138" @default.
• W2020771285 startingPage "132" @default.
• W2020771285 abstract "Pathological gambling (PG) is a disorder classified as an impulse control disorder (DSM-IV) bridging impulsive, compulsive and addictive behaviors. The striatum and thalamus are supposed to be involved in the pathophysiological substrate of these behaviors. An increased relative glucose metabolic rate (rGMR) in patients with a diagnosis of PG had previously been reported in the medial and orbitofrontal cortex. We extended our studies to include functional alterations of the striatum and thalamus in a cohort of patients with PG before and after treatment with lithium.Twenty-one patients with PG who met lifetime comorbid bipolar spectrum diagnoses and a comparison group of 21 age- and sex-matched controls underwent a baseline positron emission tomography (PET) scan. Sixteen of these patients entered a randomized double-blind placebo-controlled parallel-group-design trial of lithium and underwent a follow-up PET scan at week 10. Anatomical MRI were obtained and the structures outlined on consecutive axial slices. These individual hand-drawn templates were used to identify structures on the PET scan of each patient, and the rGMR was measured.The PG patients had a decrement of the rGMR in the ventral parts of the striatum and thalamus, and an increment of the rGMR in the dorsal parts as compared with the controls. Lithium treatment increased the ventral caudate rGMR to a trend level in the patients, but had no effect on the metabolism of either the putamen or the thalamus.Because of their extensive connectivity to the frontal cortex, striatal and thalamic functional alteration may contribute to faulty decision making processes in PG patients. By increasing the ventral rGMR of the caudate nucleus, lithium treatment may reduce cognitive dysfunction and symptoms in PG patients." @default.
• W2020771285 created "2016-06-24" @default.
• W2020771285 creator A5003010692 @default.
• W2020771285 creator A5019862707 @default.
• W2020771285 creator A5022759865 @default.
• W2020771285 creator A5025914671 @default.
• W2020771285 creator A5037040517 @default.
• W2020771285 creator A5049831926 @default.
• W2020771285 creator A5076433636 @default.
• W2020771285 date "2010-01-01" @default.
• W2020771285 modified "2023-09-27" @default.
• W2020771285 title "Basal Ganglia Activity in Pathological Gambling: A Fluorodeoxyglucose-Positron Emission Tomography Study" @default.
• W2020771285 cites W1498104517 @default.
• W2020771285 cites W1617955079 @default.
• W2020771285 cites W1863336976 @default.
• W2020771285 cites W1964953085 @default.
• W2020771285 cites W1980043955 @default.
• W2020771285 cites W1987326457 @default.
• W2020771285 cites W1990332580 @default.
• W2020771285 cites W1991688849 @default.
• W2020771285 cites W1994892862 @default.
• W2020771285 cites W1994893189 @default.
• W2020771285 cites W1999973368 @default.
• W2020771285 cites W2001427305 @default.
• W2020771285 cites W2004026761 @default.
• W2020771285 cites W2019656315 @default.
• W2020771285 cites W2029607371 @default.
• W2020771285 cites W2032724628 @default.
• W2020771285 cites W2043806828 @default.
• W2020771285 cites W2051809205 @default.
• W2020771285 cites W2058578514 @default.
• W2020771285 cites W2070780907 @default.
• W2020771285 cites W2080655347 @default.
• W2020771285 cites W2084388248 @default.
• W2020771285 cites W2099652807 @default.
• W2020771285 cites W2105389170 @default.
• W2020771285 cites W2112168582 @default.
• W2020771285 cites W2116905575 @default.
• W2020771285 cites W2122039482 @default.
• W2020771285 cites W2124677417 @default.
• W2020771285 cites W2127350926 @default.
• W2020771285 cites W2136550122 @default.
• W2020771285 cites W2138458769 @default.
• W2020771285 cites W2138718114 @default.
• W2020771285 cites W2141927127 @default.
• W2020771285 cites W2152962921 @default.
• W2020771285 cites W2165626582 @default.
• W2020771285 cites W2165881238 @default.
• W2020771285 cites W2166459776 @default.
• W2020771285 cites W2400519190 @default.
• W2020771285 cites W3127623214 @default.
• W2020771285 doi "https://doi.org/10.1159/000317286" @default.
• W2020771285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20588072" @default.
• W2020771285 hasPublicationYear "2010" @default.
• W2020771285 type Work @default.
• W2020771285 sameAs 2020771285 @default.
• W2020771285 citedByCount "21" @default.
• W2020771285 countsByYear W20207712852012 @default.
• W2020771285 countsByYear W20207712852013 @default.
• W2020771285 countsByYear W20207712852014 @default.
• W2020771285 countsByYear W20207712852015 @default.
• W2020771285 countsByYear W20207712852017 @default.
• W2020771285 countsByYear W20207712852020 @default.
• W2020771285 countsByYear W20207712852021 @default.
• W2020771285 countsByYear W20207712852022 @default.
• W2020771285 countsByYear W20207712852023 @default.
• W2020771285 crossrefType "journal-article" @default.
• W2020771285 hasAuthorship W2020771285A5003010692 @default.
• W2020771285 hasAuthorship W2020771285A5019862707 @default.
• W2020771285 hasAuthorship W2020771285A5022759865 @default.
• W2020771285 hasAuthorship W2020771285A5025914671 @default.
• W2020771285 hasAuthorship W2020771285A5037040517 @default.
• W2020771285 hasAuthorship W2020771285A5049831926 @default.
• W2020771285 hasAuthorship W2020771285A5076433636 @default.
• W2020771285 hasConcept C126322002 @default.
• W2020771285 hasConcept C137183658 @default.
• W2020771285 hasConcept C15744967 @default.
• W2020771285 hasConcept C169760540 @default.
• W2020771285 hasConcept C169900460 @default.
• W2020771285 hasConcept C2775842073 @default.
• W2020771285 hasConcept C2776552330 @default.
• W2020771285 hasConcept C2776559556 @default.
• W2020771285 hasConcept C2776743251 @default.
• W2020771285 hasConcept C2777650357 @default.
• W2020771285 hasConcept C2778187257 @default.
• W2020771285 hasConcept C2779246727 @default.
• W2020771285 hasConcept C2779714222 @default.
• W2020771285 hasConcept C2780062018 @default.
• W2020771285 hasConcept C2780948874 @default.
• W2020771285 hasConcept C2781195155 @default.
• W2020771285 hasConcept C2781423529 @default.
• W2020771285 hasConcept C2989005 @default.
• W2020771285 hasConcept C513476851 @default.
• W2020771285 hasConcept C529278444 @default.
• W2020771285 hasConcept C71924100 @default.
• W2020771285 hasConceptScore W2020771285C126322002 @default.
• W2020771285 hasConceptScore W2020771285C137183658 @default.
• W2020771285 hasConceptScore W2020771285C15744967 @default.

• next