FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020772078> ?p ?o ?g. }

• W2020772078 endingPage "211" @default.
• W2020772078 startingPage "203" @default.
• W2020772078 abstract "Although basal circulating levels of individual islet cell hormones have been measured, few studies compared the molar ratios of the major hormones secreted by the endocrine pancreas. This study examined the basal levels of four major islet hormones: insulin, C-peptide (C-P), glucagon (G), and pancreatic polypeptide (PP) in normal subjects, in organ donors with brain death, and in the isolated perfused human pancreas. Basal blood samples were taken from normal, fasted control subjects (NCs). Pancreata were obtained from 17 organ donors (ODs) with donor portal vein (DPV) and radial arterial (DRA) blood samples taken before organ procurement. Single-pass perfusion was performed on the procured pancreata, and after rewarming and equilibration, basal samples were collected from the splenic vein (SV) for 30 min. Radioimmunoassays of insulin, C-P, G, and PP were performed on all samples, and basal levels of all hormones were expressed as a common unit, femtomoles per milliliter. The data suggest that in the basal state, these four major islet hormones circulate in a relatively constant molar ratio. The ratio of the hormones is altered in brain death and with in vitro perfusion of the pancreas. The isolated perfused human pancreas secretes a relatively constant molar ratio of these hormones; however, this ratio is markedly different from the circulating ratio seen in either the NC group or the OD group. We conclude that a relatively constant hormonal milieu is secreted from the normal endocrine pancreas, and this hormonal milieu is altered after brain death and with isolation and perfusion of the human pancreas." @default.
• W2020772078 created "2016-06-24" @default.
• W2020772078 creator A5001257200 @default.
• W2020772078 creator A5007027360 @default.
• W2020772078 creator A5009788566 @default.
• W2020772078 creator A5015526581 @default.
• W2020772078 creator A5048362732 @default.
• W2020772078 creator A5049908078 @default.
• W2020772078 creator A5085382063 @default.
• W2020772078 date "2000-08-01" @default.
• W2020772078 modified "2023-09-25" @default.
• W2020772078 title "The Circulating Hormonal Milieu of the Endocrine Pancreas in Healthy Individuals, Organ Donors, and the Isolated Perfused Human Pancreas" @default.
• W2020772078 cites W1483080261 @default.
• W2020772078 cites W1964787413 @default.
• W2020772078 cites W1965152718 @default.
• W2020772078 cites W1965305294 @default.
• W2020772078 cites W1968300734 @default.
• W2020772078 cites W1971271157 @default.
• W2020772078 cites W1971779167 @default.
• W2020772078 cites W1978944519 @default.
• W2020772078 cites W1981565955 @default.
• W2020772078 cites W1982988311 @default.
• W2020772078 cites W1983498250 @default.
• W2020772078 cites W1985399798 @default.
• W2020772078 cites W1985696432 @default.
• W2020772078 cites W1987394161 @default.
• W2020772078 cites W1992107867 @default.
• W2020772078 cites W1993112795 @default.
• W2020772078 cites W1994972342 @default.
• W2020772078 cites W1995778527 @default.
• W2020772078 cites W1997265774 @default.
• W2020772078 cites W1997915932 @default.
• W2020772078 cites W2001040302 @default.
• W2020772078 cites W2001939843 @default.
• W2020772078 cites W2002255694 @default.
• W2020772078 cites W2009724144 @default.
• W2020772078 cites W2010301061 @default.
• W2020772078 cites W2012581755 @default.
• W2020772078 cites W2015265968 @default.
• W2020772078 cites W2015327999 @default.
• W2020772078 cites W2022941527 @default.
• W2020772078 cites W2024717536 @default.
• W2020772078 cites W2034640027 @default.
• W2020772078 cites W2035281757 @default.
• W2020772078 cites W2037620637 @default.
• W2020772078 cites W2038583764 @default.
• W2020772078 cites W2044887858 @default.
• W2020772078 cites W2045962469 @default.
• W2020772078 cites W2046917110 @default.
• W2020772078 cites W2047314746 @default.
• W2020772078 cites W2048287169 @default.
• W2020772078 cites W2048440462 @default.
• W2020772078 cites W2048679304 @default.
• W2020772078 cites W2048914685 @default.
• W2020772078 cites W2051090017 @default.
• W2020772078 cites W2060468612 @default.
• W2020772078 cites W2071407279 @default.
• W2020772078 cites W2074580268 @default.
• W2020772078 cites W2078376666 @default.
• W2020772078 cites W2078463727 @default.
• W2020772078 cites W2079028200 @default.
• W2020772078 cites W2079820067 @default.
• W2020772078 cites W2080186062 @default.
• W2020772078 cites W2086098212 @default.
• W2020772078 cites W2086812081 @default.
• W2020772078 cites W2088707612 @default.
• W2020772078 cites W2092643830 @default.
• W2020772078 cites W2099996883 @default.
• W2020772078 cites W2100728669 @default.
• W2020772078 cites W2102046813 @default.
• W2020772078 cites W2102478516 @default.
• W2020772078 cites W2103290081 @default.
• W2020772078 cites W2104564587 @default.
• W2020772078 cites W2113530540 @default.
• W2020772078 cites W2114813940 @default.
• W2020772078 cites W2115341688 @default.
• W2020772078 cites W2125591445 @default.
• W2020772078 cites W2134101879 @default.
• W2020772078 cites W2145609865 @default.
• W2020772078 cites W2146415791 @default.
• W2020772078 cites W2148095606 @default.
• W2020772078 cites W214907179 @default.
• W2020772078 cites W2151287536 @default.
• W2020772078 cites W2151522859 @default.
• W2020772078 cites W2155009850 @default.
• W2020772078 cites W2157094152 @default.
• W2020772078 cites W2159718638 @default.
• W2020772078 cites W2163290854 @default.
• W2020772078 cites W2164159356 @default.
• W2020772078 cites W2277072105 @default.
• W2020772078 cites W2319728719 @default.
• W2020772078 cites W2327656148 @default.
• W2020772078 cites W2328089478 @default.
• W2020772078 cites W2329762963 @default.
• W2020772078 cites W2332286485 @default.
• W2020772078 cites W2342294330 @default.
• W2020772078 cites W2409586526 @default.
• W2020772078 cites W2416327809 @default.

• next