Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020794171> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2020794171 endingPage "5" @default.
- W2020794171 startingPage "1" @default.
- W2020794171 abstract "Redox state-dependent changes in the relative orientation of the phenol side chain and the peptide group in model tyrosine have been characterized using specific 2H isotopic labelling and X-band electron paramagnetic resonance (EPR) spectroscopy. Tyrosyl radicals were generated by UV photolysis of tyrosine trapped in rigid polycrystalline basic-aqueous medium at T < or = 170 K. Ring-2H(4) and beta-2H(2) substitutions on tyrosine were used to enhance the lineshape contributions from beta-hydrogen or ring-hydrogen hyperfine interactions, respectively. The EPR lineshape at 120 K of the trapped ring-2H(4)-tyrosyl radical is altered dramatically after annealing at 235 K. In contrast, the lineshape of the beta-2H(2)-tyrosyl radical is impervious to annealing. The effect of annealing on the lineshape therefore arises from a change in the isotropic hyperfine coupling between unpaired pi-electron spin density at the ring carbon atom C(1) and the beta-hydrogen nuclei, which is caused by rotational relaxation of the ring and peptide group about the C(1)-C(beta) bond. EPR simulations indicate angular distributions of the peptide group (R-) of 0 degrees < or = theta(R) < or = 30 degrees and 0 degrees < or = theta(R)< or = 18 degrees in the rigid and relaxed radical states, respectively. Redox-induced changes in the C(1)-C(beta) rotamer distribution must be accounted for in assessments of stable amino acid side chain equilibrium structures, and may influence catalytic tyrosyl radical/tyrosine function in enzymes." @default.
- W2020794171 created "2016-06-24" @default.
- W2020794171 creator A5010577972 @default.
- W2020794171 creator A5020270612 @default.
- W2020794171 date "2001-02-01" @default.
- W2020794171 modified "2023-10-14" @default.
- W2020794171 title "Redox state dependence of rotamer distributions in tyrosine and neutral tyrosyl radical" @default.
- W2020794171 cites W1553119709 @default.
- W2020794171 cites W1979798983 @default.
- W2020794171 cites W1993090378 @default.
- W2020794171 cites W2000713880 @default.
- W2020794171 cites W2024610281 @default.
- W2020794171 cites W2025786614 @default.
- W2020794171 cites W2027189612 @default.
- W2020794171 cites W2027357772 @default.
- W2020794171 cites W2027484947 @default.
- W2020794171 cites W2032839609 @default.
- W2020794171 cites W2040572237 @default.
- W2020794171 cites W2047167565 @default.
- W2020794171 cites W2055925827 @default.
- W2020794171 cites W2065761387 @default.
- W2020794171 cites W2068589663 @default.
- W2020794171 cites W2082326383 @default.
- W2020794171 cites W2082579379 @default.
- W2020794171 cites W2091149099 @default.
- W2020794171 cites W2095550977 @default.
- W2020794171 cites W2147121758 @default.
- W2020794171 doi "https://doi.org/10.1016/s0167-4838(00)00289-2" @default.
- W2020794171 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11342025" @default.
- W2020794171 hasPublicationYear "2001" @default.
- W2020794171 type Work @default.
- W2020794171 sameAs 2020794171 @default.
- W2020794171 citedByCount "11" @default.
- W2020794171 countsByYear W20207941712016 @default.
- W2020794171 crossrefType "journal-article" @default.
- W2020794171 hasAuthorship W2020794171A5010577972 @default.
- W2020794171 hasAuthorship W2020794171A5020270612 @default.
- W2020794171 hasConcept C121332964 @default.
- W2020794171 hasConcept C131538251 @default.
- W2020794171 hasConcept C139066938 @default.
- W2020794171 hasConcept C178790620 @default.
- W2020794171 hasConcept C184779094 @default.
- W2020794171 hasConcept C185592680 @default.
- W2020794171 hasConcept C186927785 @default.
- W2020794171 hasConcept C18705241 @default.
- W2020794171 hasConcept C187961010 @default.
- W2020794171 hasConcept C204921945 @default.
- W2020794171 hasConcept C32909587 @default.
- W2020794171 hasConcept C46141821 @default.
- W2020794171 hasConcept C521977710 @default.
- W2020794171 hasConcept C75473681 @default.
- W2020794171 hasConcept C8010536 @default.
- W2020794171 hasConceptScore W2020794171C121332964 @default.
- W2020794171 hasConceptScore W2020794171C131538251 @default.
- W2020794171 hasConceptScore W2020794171C139066938 @default.
- W2020794171 hasConceptScore W2020794171C178790620 @default.
- W2020794171 hasConceptScore W2020794171C184779094 @default.
- W2020794171 hasConceptScore W2020794171C185592680 @default.
- W2020794171 hasConceptScore W2020794171C186927785 @default.
- W2020794171 hasConceptScore W2020794171C18705241 @default.
- W2020794171 hasConceptScore W2020794171C187961010 @default.
- W2020794171 hasConceptScore W2020794171C204921945 @default.
- W2020794171 hasConceptScore W2020794171C32909587 @default.
- W2020794171 hasConceptScore W2020794171C46141821 @default.
- W2020794171 hasConceptScore W2020794171C521977710 @default.
- W2020794171 hasConceptScore W2020794171C75473681 @default.
- W2020794171 hasConceptScore W2020794171C8010536 @default.
- W2020794171 hasIssue "1-2" @default.
- W2020794171 hasLocation W20207941711 @default.
- W2020794171 hasLocation W20207941712 @default.
- W2020794171 hasOpenAccess W2020794171 @default.
- W2020794171 hasPrimaryLocation W20207941711 @default.
- W2020794171 hasRelatedWork W1618869875 @default.
- W2020794171 hasRelatedWork W2030548898 @default.
- W2020794171 hasRelatedWork W2033949665 @default.
- W2020794171 hasRelatedWork W2034406201 @default.
- W2020794171 hasRelatedWork W2047625142 @default.
- W2020794171 hasRelatedWork W2050873319 @default.
- W2020794171 hasRelatedWork W2084759244 @default.
- W2020794171 hasRelatedWork W2524055164 @default.
- W2020794171 hasRelatedWork W2555528704 @default.
- W2020794171 hasRelatedWork W2563367549 @default.
- W2020794171 hasVolume "1545" @default.
- W2020794171 isParatext "false" @default.
- W2020794171 isRetracted "false" @default.
- W2020794171 magId "2020794171" @default.
- W2020794171 workType "article" @default.