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- W2020804447 abstract "Vascular system is constituted by a complex and articulate network, e.g. arteries, arterioles, venules and veins, that requires a high degree of coordination between different elemental cell types. Proteinase-activated receptors (PARs) constitute a recent described family of 7-transmembrane G protein-coupled receptors that are activated by proteolysis. In recent years several evidence have been accumulated for an involvement of this receptor in the response to endothelial injury in vitro and in vivo experimental settings suggesting a role for PAR2 in the pathophysiology of cardiovascular system. This review will deal with the role of PAR2 receptor in the cardiovascular system analyzing both in vivo and in vitro published data. In particular this review will deal with the role of this receptor in vascular reactivity, ischemia/reperfusion injury, coronary atherosclerotic lesions and angiogenesis." @default.
- W2020804447 created "2016-06-24" @default.
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- W2020804447 creator A5066988395 @default.
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- W2020804447 date "2005-10-01" @default.
- W2020804447 modified "2023-09-28" @default.
- W2020804447 title "Protease-activated receptor-2 (PAR2) in cardiovascular system" @default.
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- W2020804447 doi "https://doi.org/10.1016/j.vph.2005.07.009" @default.
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