Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020846075> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2020846075 endingPage "487" @default.
- W2020846075 startingPage "486" @default.
- W2020846075 abstract "The resurgence of human African trypanosomiasis (HAT), coupled with an increased incidence of drug resistance, is of concern. We report a quick, simple, and sensitive test for identification of parasites resistant to melarsoprol, the main drug used to treat late stage HAT. Resistant parasites are defective in a plasma membrane transporter responsible for drug uptake. The same transporter carries the fluorescent diamidine DB99 (2,5-bis-(4-amidinophenyl)-3,4-dimethylfuran) into trypanosomes. The two DNA-containing structures in the trypanosome--the nucleus and the kinetoplast--begin to fluoresce within 1 min of introduction of DB99, unless drug resistant." @default.
- W2020846075 created "2016-06-24" @default.
- W2020846075 creator A5005584147 @default.
- W2020846075 creator A5019942523 @default.
- W2020846075 creator A5027025238 @default.
- W2020846075 creator A5050874457 @default.
- W2020846075 creator A5057850926 @default.
- W2020846075 creator A5062218408 @default.
- W2020846075 creator A5073175338 @default.
- W2020846075 creator A5080123057 @default.
- W2020846075 creator A5088222987 @default.
- W2020846075 date "2005-08-01" @default.
- W2020846075 modified "2023-10-02" @default.
- W2020846075 title "Detection of arsenical drug resistance in Trypanosoma brucei with a simple fluorescence test" @default.
- W2020846075 cites W1971577029 @default.
- W2020846075 cites W1979094234 @default.
- W2020846075 cites W2017857143 @default.
- W2020846075 cites W2134012524 @default.
- W2020846075 cites W4211252435 @default.
- W2020846075 doi "https://doi.org/10.1016/s0140-6736(05)66793-1" @default.
- W2020846075 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16084257" @default.
- W2020846075 hasPublicationYear "2005" @default.
- W2020846075 type Work @default.
- W2020846075 sameAs 2020846075 @default.
- W2020846075 citedByCount "52" @default.
- W2020846075 countsByYear W20208460752012 @default.
- W2020846075 countsByYear W20208460752013 @default.
- W2020846075 countsByYear W20208460752014 @default.
- W2020846075 countsByYear W20208460752015 @default.
- W2020846075 countsByYear W20208460752016 @default.
- W2020846075 countsByYear W20208460752017 @default.
- W2020846075 countsByYear W20208460752018 @default.
- W2020846075 countsByYear W20208460752019 @default.
- W2020846075 countsByYear W20208460752020 @default.
- W2020846075 countsByYear W20208460752023 @default.
- W2020846075 crossrefType "journal-article" @default.
- W2020846075 hasAuthorship W2020846075A5005584147 @default.
- W2020846075 hasAuthorship W2020846075A5019942523 @default.
- W2020846075 hasAuthorship W2020846075A5027025238 @default.
- W2020846075 hasAuthorship W2020846075A5050874457 @default.
- W2020846075 hasAuthorship W2020846075A5057850926 @default.
- W2020846075 hasAuthorship W2020846075A5062218408 @default.
- W2020846075 hasAuthorship W2020846075A5073175338 @default.
- W2020846075 hasAuthorship W2020846075A5080123057 @default.
- W2020846075 hasAuthorship W2020846075A5088222987 @default.
- W2020846075 hasConcept C104317684 @default.
- W2020846075 hasConcept C114851261 @default.
- W2020846075 hasConcept C149011108 @default.
- W2020846075 hasConcept C159047783 @default.
- W2020846075 hasConcept C185592680 @default.
- W2020846075 hasConcept C2776027055 @default.
- W2020846075 hasConcept C2778143080 @default.
- W2020846075 hasConcept C2778792689 @default.
- W2020846075 hasConcept C2779502636 @default.
- W2020846075 hasConcept C2779549974 @default.
- W2020846075 hasConcept C2780035454 @default.
- W2020846075 hasConcept C552990157 @default.
- W2020846075 hasConcept C55493867 @default.
- W2020846075 hasConcept C86803240 @default.
- W2020846075 hasConcept C89423630 @default.
- W2020846075 hasConcept C98274493 @default.
- W2020846075 hasConceptScore W2020846075C104317684 @default.
- W2020846075 hasConceptScore W2020846075C114851261 @default.
- W2020846075 hasConceptScore W2020846075C149011108 @default.
- W2020846075 hasConceptScore W2020846075C159047783 @default.
- W2020846075 hasConceptScore W2020846075C185592680 @default.
- W2020846075 hasConceptScore W2020846075C2776027055 @default.
- W2020846075 hasConceptScore W2020846075C2778143080 @default.
- W2020846075 hasConceptScore W2020846075C2778792689 @default.
- W2020846075 hasConceptScore W2020846075C2779502636 @default.
- W2020846075 hasConceptScore W2020846075C2779549974 @default.
- W2020846075 hasConceptScore W2020846075C2780035454 @default.
- W2020846075 hasConceptScore W2020846075C552990157 @default.
- W2020846075 hasConceptScore W2020846075C55493867 @default.
- W2020846075 hasConceptScore W2020846075C86803240 @default.
- W2020846075 hasConceptScore W2020846075C89423630 @default.
- W2020846075 hasConceptScore W2020846075C98274493 @default.
- W2020846075 hasIssue "9484" @default.
- W2020846075 hasLocation W20208460751 @default.
- W2020846075 hasLocation W20208460752 @default.
- W2020846075 hasOpenAccess W2020846075 @default.
- W2020846075 hasPrimaryLocation W20208460751 @default.
- W2020846075 hasRelatedWork W1983053466 @default.
- W2020846075 hasRelatedWork W1987652678 @default.
- W2020846075 hasRelatedWork W2020846075 @default.
- W2020846075 hasRelatedWork W2043973119 @default.
- W2020846075 hasRelatedWork W2065233446 @default.
- W2020846075 hasRelatedWork W2128993663 @default.
- W2020846075 hasRelatedWork W2737736096 @default.
- W2020846075 hasRelatedWork W2792563781 @default.
- W2020846075 hasRelatedWork W2804874694 @default.
- W2020846075 hasRelatedWork W4220814734 @default.
- W2020846075 hasVolume "366" @default.
- W2020846075 isParatext "false" @default.
- W2020846075 isRetracted "false" @default.
- W2020846075 magId "2020846075" @default.
- W2020846075 workType "article" @default.