Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020861458> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2020861458 endingPage "183" @default.
- W2020861458 startingPage "175" @default.
- W2020861458 abstract "More than one century after the discovery of trisomy 21, the molecular mechanisms underlying the complex phenotype associated with Down syndrome (DS) remain unknown. Up to now, the molecular consequences of gene-dosage imbalance have been mainly investigated by the definition of DS critical regions, based on phenotype-genotype correlations established for rare cases of partial trisomy 21. Recently, the generation of trisomic mouse models has opened interesting possibilities for studying components of the DS phenotype, addressing in particular the cerebellar pathology. The complete DNA sequence, clone map, and gene catalogue of chromosome 21 offers new molecular tools for revisiting phenotype-genotype correlations and for dissecting the molecular bases of DS pathogenesis, using strategic technologies that will allow to define molecular profiles of trisomy 21." @default.
- W2020861458 created "2016-06-24" @default.
- W2020861458 creator A5054096019 @default.
- W2020861458 creator A5071739380 @default.
- W2020861458 date "2000-12-01" @default.
- W2020861458 modified "2023-09-27" @default.
- W2020861458 title "Human chromosome 21 sequence: impact for the molecular genetics of Down syndrome" @default.
- W2020861458 cites W120281564 @default.
- W2020861458 cites W12038155 @default.
- W2020861458 cites W1514297589 @default.
- W2020861458 cites W1977971284 @default.
- W2020861458 cites W1987607749 @default.
- W2020861458 cites W1995344309 @default.
- W2020861458 cites W2017199287 @default.
- W2020861458 cites W2023511811 @default.
- W2020861458 cites W2027036934 @default.
- W2020861458 cites W2038934257 @default.
- W2020861458 cites W2045568306 @default.
- W2020861458 cites W2051859228 @default.
- W2020861458 cites W2054351623 @default.
- W2020861458 cites W2063964767 @default.
- W2020861458 cites W2084233122 @default.
- W2020861458 cites W2088291608 @default.
- W2020861458 cites W2093636816 @default.
- W2020861458 cites W2107607304 @default.
- W2020861458 cites W2126800086 @default.
- W2020861458 cites W2149852014 @default.
- W2020861458 cites W2419393271 @default.
- W2020861458 doi "https://doi.org/10.1002/1438-826x(200012)1:5/6<175::aid-gnfd175>3.0.co;2-6" @default.
- W2020861458 hasPublicationYear "2000" @default.
- W2020861458 type Work @default.
- W2020861458 sameAs 2020861458 @default.
- W2020861458 citedByCount "5" @default.
- W2020861458 crossrefType "journal-article" @default.
- W2020861458 hasAuthorship W2020861458A5054096019 @default.
- W2020861458 hasAuthorship W2020861458A5071739380 @default.
- W2020861458 hasConcept C104317684 @default.
- W2020861458 hasConcept C127716648 @default.
- W2020861458 hasConcept C137555145 @default.
- W2020861458 hasConcept C200844832 @default.
- W2020861458 hasConcept C204315192 @default.
- W2020861458 hasConcept C2776229224 @default.
- W2020861458 hasConcept C2779954681 @default.
- W2020861458 hasConcept C30481170 @default.
- W2020861458 hasConcept C54355233 @default.
- W2020861458 hasConcept C70721500 @default.
- W2020861458 hasConcept C86803240 @default.
- W2020861458 hasConceptScore W2020861458C104317684 @default.
- W2020861458 hasConceptScore W2020861458C127716648 @default.
- W2020861458 hasConceptScore W2020861458C137555145 @default.
- W2020861458 hasConceptScore W2020861458C200844832 @default.
- W2020861458 hasConceptScore W2020861458C204315192 @default.
- W2020861458 hasConceptScore W2020861458C2776229224 @default.
- W2020861458 hasConceptScore W2020861458C2779954681 @default.
- W2020861458 hasConceptScore W2020861458C30481170 @default.
- W2020861458 hasConceptScore W2020861458C54355233 @default.
- W2020861458 hasConceptScore W2020861458C70721500 @default.
- W2020861458 hasConceptScore W2020861458C86803240 @default.
- W2020861458 hasIssue "5-6" @default.
- W2020861458 hasLocation W20208614581 @default.
- W2020861458 hasOpenAccess W2020861458 @default.
- W2020861458 hasPrimaryLocation W20208614581 @default.
- W2020861458 hasRelatedWork W1647925169 @default.
- W2020861458 hasRelatedWork W1997381668 @default.
- W2020861458 hasRelatedWork W2041524245 @default.
- W2020861458 hasRelatedWork W2064358122 @default.
- W2020861458 hasRelatedWork W2082980172 @default.
- W2020861458 hasRelatedWork W2104006968 @default.
- W2020861458 hasRelatedWork W2117684960 @default.
- W2020861458 hasRelatedWork W2160446754 @default.
- W2020861458 hasRelatedWork W2597823111 @default.
- W2020861458 hasRelatedWork W6875533 @default.
- W2020861458 hasVolume "1" @default.
- W2020861458 isParatext "false" @default.
- W2020861458 isRetracted "false" @default.
- W2020861458 magId "2020861458" @default.
- W2020861458 workType "article" @default.