FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020873906> ?p ?o ?g. }

• W2020873906 endingPage "520" @default.
• W2020873906 startingPage "512" @default.
• W2020873906 abstract "In brain, most L-tryptophan is metabolized to indoleamines, whereas in systemic tissues L-tryptophan is catabolized to kynurenine pathway metabolites. Among these latter compounds are: quinolinic acid, an N-methyl-D-aspartate receptor agonist; kynurenic acid, an antagonist of excitatory amino acid receptors that also reduces quinolinic acid-mediated neurotoxicity; and L-kynurenine, a possible convulsant. Because the metabolism of L-tryptophan through the kynurenine pathway is dependent upon adequate nutrition, we sought to determine whether the impaired nutrition characteristic of eating-disordered patients might be associated with specific disturbances in this metabolic pathway. Cerebrospinal fluid levels of L-tryptophan, quinolinic acid, kynurenic acid, L-kynurenine, and 5-hydroxyindoleacetic acid were measured in medication-free female patients meeting DSM-III-R criteria for either anorexia nervosa (n = 10) or normal-weight bulimia nervosa (n = 22), studied at varying stages of nutritional recovery. Eight healthy, normal-weight females served as a comparison group. Cerebrospinal fluid levels of kynurenic acid were significantly reduced in underweight anorectics, compared to normal females, but returned to normal values with restoration of normal body weight. Although cerebrospinal fluid quinolinic acid levels were not different from controls, the ratio of quinolinic acid to kynurenic acid was significantly increased during the underweight phase of anorexia nervosa. Furthermore, in the eating-disordered patients, kynurenic acid levels in cerebrospinal fluid correlated positively with percent-of-population average body weight.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2020873906 created "2016-06-24" @default.
• W2020873906 creator A5005497098 @default.
• W2020873906 creator A5016323257 @default.
• W2020873906 creator A5048595396 @default.
• W2020873906 creator A5069617316 @default.
• W2020873906 creator A5078128383 @default.
• W2020873906 date "1995-04-01" @default.
• W2020873906 modified "2023-10-16" @default.
• W2020873906 title "Cerebrospinal fluid levels of kynurenine pathway metabolites in patients with eating disorders: Relation to clinical and biochemical variable" @default.
• W2020873906 cites W1487888278 @default.
• W2020873906 cites W1543127122 @default.
• W2020873906 cites W1605075022 @default.
• W2020873906 cites W1882953667 @default.
• W2020873906 cites W1969388943 @default.
• W2020873906 cites W1971946958 @default.
• W2020873906 cites W1972183007 @default.
• W2020873906 cites W1976364490 @default.
• W2020873906 cites W1993419219 @default.
• W2020873906 cites W1998347917 @default.
• W2020873906 cites W2010145371 @default.
• W2020873906 cites W2011447282 @default.
• W2020873906 cites W2012906643 @default.
• W2020873906 cites W2014572571 @default.
• W2020873906 cites W2016759315 @default.
• W2020873906 cites W2017738672 @default.
• W2020873906 cites W2018073475 @default.
• W2020873906 cites W2042043007 @default.
• W2020873906 cites W2044981704 @default.
• W2020873906 cites W2051353156 @default.
• W2020873906 cites W2053124968 @default.
• W2020873906 cites W2063460846 @default.
• W2020873906 cites W2067292092 @default.
• W2020873906 cites W2084990956 @default.
• W2020873906 cites W2087484317 @default.
• W2020873906 cites W2087539536 @default.
• W2020873906 cites W2090352316 @default.
• W2020873906 cites W2091578245 @default.
• W2020873906 cites W2100040827 @default.
• W2020873906 cites W2106625755 @default.
• W2020873906 cites W2137080736 @default.
• W2020873906 cites W2145302977 @default.
• W2020873906 cites W2334353699 @default.
• W2020873906 cites W2742265051 @default.
• W2020873906 doi "https://doi.org/10.1016/0006-3223(94)00173-z" @default.
• W2020873906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7542489" @default.
• W2020873906 hasPublicationYear "1995" @default.
• W2020873906 type Work @default.
• W2020873906 sameAs 2020873906 @default.
• W2020873906 citedByCount "30" @default.
• W2020873906 countsByYear W20208739062013 @default.
• W2020873906 countsByYear W20208739062016 @default.
• W2020873906 countsByYear W20208739062017 @default.
• W2020873906 countsByYear W20208739062019 @default.
• W2020873906 countsByYear W20208739062020 @default.
• W2020873906 countsByYear W20208739062021 @default.
• W2020873906 countsByYear W20208739062022 @default.
• W2020873906 countsByYear W20208739062023 @default.
• W2020873906 crossrefType "journal-article" @default.
• W2020873906 hasAuthorship W2020873906A5005497098 @default.
• W2020873906 hasAuthorship W2020873906A5016323257 @default.
• W2020873906 hasAuthorship W2020873906A5048595396 @default.
• W2020873906 hasAuthorship W2020873906A5069617316 @default.
• W2020873906 hasAuthorship W2020873906A5078128383 @default.
• W2020873906 hasConcept C118552586 @default.
• W2020873906 hasConcept C126322002 @default.
• W2020873906 hasConcept C134018914 @default.
• W2020873906 hasConcept C170493617 @default.
• W2020873906 hasConcept C185592680 @default.
• W2020873906 hasConcept C2776394216 @default.
• W2020873906 hasConcept C2776706248 @default.
• W2020873906 hasConcept C2776710720 @default.
• W2020873906 hasConcept C2776841986 @default.
• W2020873906 hasConcept C2777031586 @default.
• W2020873906 hasConcept C2777503454 @default.
• W2020873906 hasConcept C2777896816 @default.
• W2020873906 hasConcept C2779491297 @default.
• W2020873906 hasConcept C2779651940 @default.
• W2020873906 hasConcept C2780221984 @default.
• W2020873906 hasConcept C2780586474 @default.
• W2020873906 hasConcept C2781121325 @default.
• W2020873906 hasConcept C29730261 @default.
• W2020873906 hasConcept C515207424 @default.
• W2020873906 hasConcept C55493867 @default.
• W2020873906 hasConcept C61174792 @default.
• W2020873906 hasConcept C71924100 @default.
• W2020873906 hasConceptScore W2020873906C118552586 @default.
• W2020873906 hasConceptScore W2020873906C126322002 @default.
• W2020873906 hasConceptScore W2020873906C134018914 @default.
• W2020873906 hasConceptScore W2020873906C170493617 @default.
• W2020873906 hasConceptScore W2020873906C185592680 @default.
• W2020873906 hasConceptScore W2020873906C2776394216 @default.
• W2020873906 hasConceptScore W2020873906C2776706248 @default.
• W2020873906 hasConceptScore W2020873906C2776710720 @default.
• W2020873906 hasConceptScore W2020873906C2776841986 @default.
• W2020873906 hasConceptScore W2020873906C2777031586 @default.
• W2020873906 hasConceptScore W2020873906C2777503454 @default.
• W2020873906 hasConceptScore W2020873906C2777896816 @default.

• next