FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2020942783> ?p ?o ?g. }

• W2020942783 endingPage "221" @default.
• W2020942783 startingPage "221" @default.
• W2020942783 abstract "The survival of CHO cells to hyperthermic treatment combined with radiation indicates that heat given either immediately before or immediately after irradiation radiosensitizers S-phase cells more than G1 cells, thus resulting in similar absolute levels of survival for each phase. No difference in effect was observed for different temperatures (42.0 to 45.5/sup 0/C) applied before irradiation in either G1 or S when times of heating were adjusted to obtain the same survival (0.5 to 0.6) from heat alone. When heat was administered after irradiation and the time between treatments was increased, repair during G1 of radiation damage which interacted with subsequent heat damage occurred over a 2-hr period. Survival increased from a synergistic level to an independent level with kinetics similar to those seen for repair between split x-ray doses. For this experiment, the heat treatments were administered at either 42.5 or 45.5/sup 0/C with times of heating adjusted to obtain the same survival (0.15) from heat alone. When cells were treated similarly in S phase using either 42.5 or 45.5/sup 0/C (survival from heat alone was 0.2), recovery from a synergistic level of survival was similar to that observed in G1; however, survival did not reach an independent levelmore » by 120 min between treatments. When relatively sublethal heat doses at either 42.5 or 45.5/sup 0/C were applied either before, during, or after irradiation, the maximum reduction in survival of asynchronous cells occurred when heat was present during and immediately following irradation, presumably due to heat increasing the fixation of radiation damage. A sixfold difference in survival was observed with about a 5-min change in the timing of radiation with respect to heating. This sensitivity of survival to changes in protocol may have considerable implications in the combined use of hyperthermia and radiation for cancer therapy.« less" @default.
• W2020942783 created "2016-06-24" @default.
• W2020942783 creator A5017488510 @default.
• W2020942783 creator A5045098217 @default.
• W2020942783 creator A5075614980 @default.
• W2020942783 date "1978-02-01" @default.
• W2020942783 modified "2023-09-30" @default.
• W2020942783 title "Combined Effects of X Irradiation and Hyperthermia on CHO Cells for Various Temperatures and Orders of Application" @default.
• W2020942783 cites W1522354384 @default.
• W2020942783 cites W1966031020 @default.
• W2020942783 cites W1976400042 @default.
• W2020942783 cites W1978661077 @default.
• W2020942783 cites W1984910189 @default.
• W2020942783 cites W2002910462 @default.
• W2020942783 cites W2006550224 @default.
• W2020942783 cites W2019789888 @default.
• W2020942783 cites W2025657536 @default.
• W2020942783 cites W2027366645 @default.
• W2020942783 cites W2034768069 @default.
• W2020942783 cites W2043402257 @default.
• W2020942783 cites W2059743397 @default.
• W2020942783 cites W2079239443 @default.
• W2020942783 cites W2082671296 @default.
• W2020942783 cites W2090833772 @default.
• W2020942783 cites W2092248711 @default.
• W2020942783 cites W2102884043 @default.
• W2020942783 cites W2107817773 @default.
• W2020942783 cites W2112222688 @default.
• W2020942783 cites W2134398178 @default.
• W2020942783 cites W2161382930 @default.
• W2020942783 cites W2256642101 @default.
• W2020942783 cites W2318429450 @default.
• W2020942783 cites W68646502 @default.
• W2020942783 doi "https://doi.org/10.2307/3574816" @default.
• W2020942783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/635107" @default.
• W2020942783 hasPublicationYear "1978" @default.
• W2020942783 type Work @default.
• W2020942783 sameAs 2020942783 @default.
• W2020942783 citedByCount "124" @default.
• W2020942783 countsByYear W20209427832013 @default.
• W2020942783 countsByYear W20209427832014 @default.
• W2020942783 countsByYear W20209427832015 @default.
• W2020942783 countsByYear W20209427832016 @default.
• W2020942783 countsByYear W20209427832017 @default.
• W2020942783 countsByYear W20209427832018 @default.
• W2020942783 countsByYear W20209427832019 @default.
• W2020942783 countsByYear W20209427832020 @default.
• W2020942783 countsByYear W20209427832021 @default.
• W2020942783 countsByYear W20209427832023 @default.
• W2020942783 crossrefType "journal-article" @default.
• W2020942783 hasAuthorship W2020942783A5017488510 @default.
• W2020942783 hasAuthorship W2020942783A5045098217 @default.
• W2020942783 hasAuthorship W2020942783A5075614980 @default.
• W2020942783 hasConcept C111337013 @default.
• W2020942783 hasConcept C121332964 @default.
• W2020942783 hasConcept C126322002 @default.
• W2020942783 hasConcept C177322064 @default.
• W2020942783 hasConcept C185544564 @default.
• W2020942783 hasConcept C185592680 @default.
• W2020942783 hasConcept C192562407 @default.
• W2020942783 hasConcept C2779949491 @default.
• W2020942783 hasConcept C2989005 @default.
• W2020942783 hasConcept C71924100 @default.
• W2020942783 hasConceptScore W2020942783C111337013 @default.
• W2020942783 hasConceptScore W2020942783C121332964 @default.
• W2020942783 hasConceptScore W2020942783C126322002 @default.
• W2020942783 hasConceptScore W2020942783C177322064 @default.
• W2020942783 hasConceptScore W2020942783C185544564 @default.
• W2020942783 hasConceptScore W2020942783C185592680 @default.
• W2020942783 hasConceptScore W2020942783C192562407 @default.
• W2020942783 hasConceptScore W2020942783C2779949491 @default.
• W2020942783 hasConceptScore W2020942783C2989005 @default.
• W2020942783 hasConceptScore W2020942783C71924100 @default.
• W2020942783 hasIssue "2" @default.
• W2020942783 hasLocation W20209427831 @default.
• W2020942783 hasLocation W20209427832 @default.
• W2020942783 hasOpenAccess W2020942783 @default.
• W2020942783 hasPrimaryLocation W20209427831 @default.
• W2020942783 hasRelatedWork W1987419628 @default.
• W2020942783 hasRelatedWork W2015250514 @default.
• W2020942783 hasRelatedWork W2027053195 @default.
• W2020942783 hasRelatedWork W2092024987 @default.
• W2020942783 hasRelatedWork W2168310623 @default.
• W2020942783 hasRelatedWork W2300581620 @default.
• W2020942783 hasRelatedWork W2325517415 @default.
• W2020942783 hasRelatedWork W2430973284 @default.
• W2020942783 hasRelatedWork W2899084033 @default.
• W2020942783 hasRelatedWork W84733317 @default.
• W2020942783 hasVolume "73" @default.
• W2020942783 isParatext "false" @default.
• W2020942783 isRetracted "false" @default.
• W2020942783 magId "2020942783" @default.
• W2020942783 workType "article" @default.