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- W2020956344 abstract "We assessed the effect of 3 h of environmental enrichment (EE) exposure per day started at different ages (3 and 18 months old) on the performance in a spatial memory task and on brain regions involved in the spatial learning (SPL) process using the principal component analysis (PCA). The animals were tested in the four-arm radial water maze (4-RAWM) for 4 days, with six daily trials. We used cytochrome c oxidase (COx) histochemistry to determine the brain oxidative metabolic changes related to age, SPL and EE. Behavioural results showed that the enriched groups, regardless of their age, achieved better performance in the spatial task. Interestingly, in the case of the distance travelled in the 4-RAWM, the effect of the EE was dependent on the age, so the young enriched group travelled a shorter distance compared to the aged enriched group. Respect to COx histochemistry results, we found that different brain mechanisms are triggered in aged rats to solve the spatial task, compared to young rats. PCA revealed the same brain functional network in both age groups, but the contribution of the brain regions involved in this network was slightly different depending on the age of the rats. Thus, in the aged group, brain regions involved in anxiety-like behaviour, such as the amygdala or the bed nucleus of the stria terminalis had more relevance; whereas in the young enriched group the frontal and the hippocampal subregions had more contribution." @default.
- W2020956344 created "2016-06-24" @default.
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- W2020956344 date "2013-09-01" @default.
- W2020956344 modified "2023-10-17" @default.
- W2020956344 title "Age-dependent effects of environmental enrichment on brain networks and spatial memory in Wistar rats" @default.
- W2020956344 cites W1930967349 @default.
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- W2020956344 cites W1969031947 @default.
- W2020956344 cites W1969077909 @default.
- W2020956344 cites W1972702742 @default.
- W2020956344 cites W1973752193 @default.
- W2020956344 cites W1975353729 @default.
- W2020956344 cites W1976258471 @default.
- W2020956344 cites W1978685355 @default.
- W2020956344 cites W1978971861 @default.
- W2020956344 cites W1979469164 @default.
- W2020956344 cites W1984200333 @default.
- W2020956344 cites W1991441586 @default.
- W2020956344 cites W1999576941 @default.
- W2020956344 cites W2002159284 @default.
- W2020956344 cites W2003041124 @default.
- W2020956344 cites W2005025961 @default.
- W2020956344 cites W2006129024 @default.
- W2020956344 cites W2007923417 @default.
- W2020956344 cites W2009006708 @default.
- W2020956344 cites W2011963405 @default.
- W2020956344 cites W2014497513 @default.
- W2020956344 cites W2017164226 @default.
- W2020956344 cites W2018800927 @default.
- W2020956344 cites W2019773050 @default.
- W2020956344 cites W2021947606 @default.
- W2020956344 cites W2021954644 @default.
- W2020956344 cites W2022068092 @default.
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- W2020956344 cites W2035128319 @default.
- W2020956344 cites W2035761443 @default.
- W2020956344 cites W2038112334 @default.
- W2020956344 cites W2039969351 @default.
- W2020956344 cites W2041457323 @default.
- W2020956344 cites W2044715983 @default.
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- W2020956344 cites W2046895321 @default.
- W2020956344 cites W2047247835 @default.
- W2020956344 cites W2052449485 @default.
- W2020956344 cites W2056816990 @default.
- W2020956344 cites W2060594053 @default.
- W2020956344 cites W2062134636 @default.
- W2020956344 cites W2064994363 @default.
- W2020956344 cites W2065843454 @default.
- W2020956344 cites W2067570041 @default.
- W2020956344 cites W2067576490 @default.
- W2020956344 cites W2067954619 @default.
- W2020956344 cites W2070604675 @default.
- W2020956344 cites W2074869456 @default.
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- W2020956344 cites W2079365178 @default.
- W2020956344 cites W2083194463 @default.
- W2020956344 cites W2085061337 @default.
- W2020956344 cites W2086255984 @default.
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- W2020956344 cites W2095622480 @default.
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- W2020956344 doi "https://doi.org/10.1016/j.neuroscience.2013.06.003" @default.
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