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- W2020967677 abstract "The synthesis and SAR of a series of substituted 1-aminotetrahydrocarbazoles with potent activity against human papillomaviruses are described. Synthetic approaches allowing for variation of the substitution pattern of the tetrahydrocarbazole are outlined and resulting changes in antiviral activity are highlighted. Several compounds with in vitro antiviral activity (W12 antiviral assay) in the low nanomolar range were identified and (1R)-6-bromo-N-[(1R)-1-phenylethyl]-2,3,4,9-tetrahydro-1H-carbazole-1-amine was selected for further evaluation." @default.
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- W2020967677 date "2009-07-01" @default.
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- W2020967677 title "Substituted tetrahydrocarbazoles with potent activity against human papillomaviruses" @default.
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- W2020967677 doi "https://doi.org/10.1016/j.bmcl.2009.05.003" @default.
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