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W2020971441 abstract "A series of potent and highly selective cyclooxygenase-2 inhibitors have been prepared by replacing the benzoyl group of indomethacin with a 4-bromobenzyl group, and by extending the acetic acid side chain. These compounds show anti-inflammatory activity in rats with no evidence of GI toxicity, even at high doses." @default.
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W2020971441 date "1996-03-01" @default.
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W2020971441 title "From indomethacin to a selective COX-2 inhibitor: Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors" @default.
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W2020971441 doi "https://doi.org/10.1016/0960-894x(96)00100-x" @default.
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