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- W2020973025 abstract "The selection of different diimines 4 a–c by alkaline earth ions from a virtual combinatorial library (VCL) is described. The products were stabilized by reduction to the diamines 6 a–c; this allowed easy analysis. The library can be directed toward different target molecules 6 a–c upon addition of alkaline earth ions with different radii. Competition experiments show the possibility of synthesizing the macrocycles 6 a, 6 b, and 6 c simultaneously when using Mg2+, Ca2+, and Ba2+ as template ions. The scope of this thermodynamically controlled, reversible approach for macrocycle syntheses is illustrated." @default.
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- W2020973025 date "2002-02-15" @default.
- W2020973025 modified "2023-10-14" @default.
- W2020973025 title "How To Synthesize Macrocycles Efficiently by Using Virtual Combinatorial Libraries" @default.
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- W2020973025 doi "https://doi.org/10.1002/1521-3765(20020215)8:4<793::aid-chem793>3.0.co;2-u" @default.
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