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- W2020978031 endingPage "268" @default.
- W2020978031 startingPage "254" @default.
- W2020978031 abstract "Mucins are a family of heavily glycosylated proteins that are the major organic components of the mucus layer, the protective layer covering the epithelial cells in many human and animal organs, including the entire gastro-intestinal tract. Microbes that can associate with mucins benefit from this interaction since they can get available nutrients, experience physico-chemical protection and adhere, resulting in increased residence time. Mucin-degrading microorganisms, which often are found in consortia, have not been extensively characterized as mucins are high molecular weight glycoproteins that are hard to study because of their size, complexity and heterogeneity. The purpose of this review is to discuss how advances in mucus and mucin research, and insight in the microbial ecology promoted our understanding of mucin degradation. Recent insight is presented in mucin structure and organization, the microorganisms known to use mucin as growth substrate, with a specific attention on Akkermansia muciniphila, and the molecular basis of microbial mucin degradation owing to availability of genome sequences." @default.
- W2020978031 created "2016-06-24" @default.
- W2020978031 creator A5021187431 @default.
- W2020978031 creator A5021942156 @default.
- W2020978031 creator A5054572740 @default.
- W2020978031 creator A5074836954 @default.
- W2020978031 creator A5077992953 @default.
- W2020978031 creator A5082852718 @default.
- W2020978031 date "2010-07-01" @default.
- W2020978031 modified "2023-10-16" @default.
- W2020978031 title "Mucin-bacterial interactions in the human oral cavity and digestive tract" @default.
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