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- W2020993665 abstract "SUMMARYThe effect of acute experimental uraemia, caused by the removal of one kidney and clamping of the renal pedicle on the other side for one and a half hours, upon the immunological responses to bovine serum albumin has been studied in the rabbit.Rabbits in a phase of severe uraemia experiencing bovine albumin for the first time show a marked delay in the elimination of this antigen from the blood stream. These animals failed to form antibody to bovine albumin during the thirteen days following primary challenge. After recovery from uraemia, these rabbits did eventually form normal amounts of antibody. It is suggested that this delay in antibody production is a “stress phenomenon.”The primary response to bovine albumin is unaffected by a phase of mild uraemia.The secondary response to this antigen is normal irrespective of whether the uraemia is mild or severe.The results presented are discussed in relation to the evidence obtained by other workers in patients suffering from both acute and chronic uraemia." @default.
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- W2020993665 date "1962-09-01" @default.
- W2020993665 modified "2023-09-23" @default.
- W2020993665 title "THE EFFECT OF ACUTE EXPERIMENTAL URAEMIA ON THE IMMUNOLOGICAL RESPONSES OF THE RABBIT TO BOVINE SERUM ALBUMIN" @default.
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- W2020993665 doi "https://doi.org/10.1111/j.1464-410x.1962.tb09456.x" @default.
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