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• W2020997237 abstract "Objective and background: To determine the utility of positron emission tomography with CT (PET‐CT) in the evaluation of non‐small cell lung cancer (NSCLC) in an Asian context where tuberculosis rates are moderately high. Methods: Case records of consecutive patients with NSCLC undergoing PET‐CT at the Singapore General Hospital over a 1‐year period were retrospectively reviewed. The authors evaluated the sensitivity and specificity of PET‐CT at their institution using surgical pathology or the tincture of time as the gold standard. Results: A total of 54 patients underwent PET‐CT during this period. Seven patients were evaluated for solitary pulmonary nodule, for which PET‐CT gave a sensitivity of 100% and specificity of 75%. There was one patient with false positive PET‐CT due to active tuberculosis. In total, 41 patients underwent PET‐CT for staging of NSCLC. There was one false positive (patient was found to have active tuberculous lymphadenitis) and one false negative for NSCLC. This gave a sensitivity of 92.3% and a specificity of 95%. Histology from the adrenal glands was available in two patients with PET‐CT that was positive for adrenal metastases. One proved to be benign whereas the other was consistent with metastasis. Two patients had PET‐CT positive for liver metastases, which was verified by histology. Two patients with positive PET‐CT for lesions in the colon turned out to be benign histologically. Conclusions: Positron emission tomography with CT for the evaluation and follow‐up of solitary pulmonary nodule and NSCLC can provide additional useful information to conventional radiology for treatment planning and a non‐invasive determination of prognosis. However, physicians need to be aware of the limitations of this imaging modality, particularly when tuberculosis has a high prevalence in the population." @default.
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• W2020997237 date "2006-01-01" @default.
• W2020997237 modified "2023-10-15" @default.
• W2020997237 title "Positron emission tomography with CT in the evaluation of non-small cell lung cancer in populations with a high prevalence of tuberculosis" @default.
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• W2020997237 doi "https://doi.org/10.1111/j.1440-1843.2006.00789.x" @default.
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