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- W2021002617 abstract "An active encapsulation method to obtain high entrapment in liposomes is described. The method harnesses the ability of dendrimer to interact with oppositely charged phospholipid and solubilize acidic drugs in their interior. The high drug entrapment in liposomes is due to the enhanced entrapment of dendrimer, which creates sink in the liposomal aqueous compartment where the methotrexate (MTX) molecules are fluxed in. The encapsulation increases with dendrimer generation. The release of bioactive was also decreased by this method. The method may be useful to entrap drugs with relatively high therapeutic dose." @default.
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- W2021002617 date "2002-01-01" @default.
- W2021002617 modified "2023-10-16" @default.
- W2021002617 title "Effect of dendrimer on entrapment and release of bioactive from liposomes" @default.
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- W2021002617 doi "https://doi.org/10.1016/s0378-5173(01)00901-2" @default.
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