FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021002926> ?p ?o ?g. }

• W2021002926 endingPage "424" @default.
• W2021002926 startingPage "419" @default.
• W2021002926 abstract "It has been suggested that hyperosmolarity may be one of the stimuli that provoke exercise-induced asthma and rhinitis. We investigated whether changes in osmolarity could result in increased levels of mediator release from nasal cells. Cells were dispersed from nasal polyps by enzymatic digestion and were incubated for 15 minutes with solutions of varying osmolarity obtained by the addition of mannitol to Hanks' balanced salt solution. After incubation was performed, cell supernatants were removed, and the release of 15-hydroxyeicosatetraenoic acid, prostaglandin2 leukotriene B4, and fibronectin was measured. Lactate dehydrogenase was measured to assess cell viability. Epithelial cells made up 40% to 60% of cells and mononuclear cells 40% to 65%. At 900 mOsm/kg H2O, which has been suggested as the osmolarity of the fluid lining the airways during exercise, we observed a significant increase (Wilcoxon W test) in the release of 15-hydroxyeicosatetraenoic acid (p < 0.008), leukotriene B4 (p < 0.008), and prostaglandin2 (p < 0.008), but no significant increase in the release of fibronectin was seen. No significant increase was seen between lactate dehydrogenase and 15-hydroxyeicosatetraenoic acid release, suggesting that the increase in mediator levels was not caused by cell death. These results show that hyperosmolar solutions can induce activation of nasal cells, which may at least partly explain rhinitis caused by exercise. (J Allergy Clin Immunol 1995;96:980–5.)" @default.
• W2021002926 created "2016-06-24" @default.
• W2021002926 creator A5052702741 @default.
• W2021002926 creator A5055599633 @default.
• W2021002926 creator A5062817966 @default.
• W2021002926 creator A5065008155 @default.
• W2021002926 creator A5070000596 @default.
• W2021002926 creator A5073415116 @default.
• W2021002926 creator A5075387555 @default.
• W2021002926 creator A5076809475 @default.
• W2021002926 date "1996-06-01" @default.
• W2021002926 modified "2023-10-18" @default.
• W2021002926 title "Stimulation of dispersed nasal polyp cells by hyperosmolar solutions" @default.
• W2021002926 cites W1835053601 @default.
• W2021002926 cites W1967820573 @default.
• W2021002926 cites W1973715395 @default.
• W2021002926 cites W1982297215 @default.
• W2021002926 cites W2003426251 @default.
• W2021002926 cites W2003855023 @default.
• W2021002926 cites W2013674196 @default.
• W2021002926 cites W2015843034 @default.
• W2021002926 cites W2016693266 @default.
• W2021002926 cites W2019813950 @default.
• W2021002926 cites W2022225439 @default.
• W2021002926 cites W2037938250 @default.
• W2021002926 cites W2039072947 @default.
• W2021002926 cites W2041778216 @default.
• W2021002926 cites W2052169710 @default.
• W2021002926 cites W2052306917 @default.
• W2021002926 cites W2060433169 @default.
• W2021002926 cites W2063121735 @default.
• W2021002926 cites W2065294999 @default.
• W2021002926 cites W2065308194 @default.
• W2021002926 cites W2100913143 @default.
• W2021002926 cites W2102824566 @default.
• W2021002926 cites W2106188734 @default.
• W2021002926 cites W2124314287 @default.
• W2021002926 cites W2130321685 @default.
• W2021002926 cites W2143951297 @default.
• W2021002926 cites W2174783702 @default.
• W2021002926 cites W2320579232 @default.
• W2021002926 cites W2403739954 @default.
• W2021002926 cites W4312545165 @default.
• W2021002926 doi "https://doi.org/10.1016/s0335-7457(96)80156-0" @default.
• W2021002926 hasPublicationYear "1996" @default.
• W2021002926 type Work @default.
• W2021002926 sameAs 2021002926 @default.
• W2021002926 citedByCount "0" @default.
• W2021002926 crossrefType "journal-article" @default.
• W2021002926 hasAuthorship W2021002926A5052702741 @default.
• W2021002926 hasAuthorship W2021002926A5055599633 @default.
• W2021002926 hasAuthorship W2021002926A5062817966 @default.
• W2021002926 hasAuthorship W2021002926A5065008155 @default.
• W2021002926 hasAuthorship W2021002926A5070000596 @default.
• W2021002926 hasAuthorship W2021002926A5073415116 @default.
• W2021002926 hasAuthorship W2021002926A5075387555 @default.
• W2021002926 hasAuthorship W2021002926A5076809475 @default.
• W2021002926 hasConcept C126322002 @default.
• W2021002926 hasConcept C129900496 @default.
• W2021002926 hasConcept C134018914 @default.
• W2021002926 hasConcept C14705128 @default.
• W2021002926 hasConcept C178790620 @default.
• W2021002926 hasConcept C181199279 @default.
• W2021002926 hasConcept C185592680 @default.
• W2021002926 hasConcept C24998067 @default.
• W2021002926 hasConcept C2776685179 @default.
• W2021002926 hasConcept C2776914184 @default.
• W2021002926 hasConcept C2777318727 @default.
• W2021002926 hasConcept C2778445172 @default.
• W2021002926 hasConcept C2778996431 @default.
• W2021002926 hasConcept C55493867 @default.
• W2021002926 hasConcept C71924100 @default.
• W2021002926 hasConceptScore W2021002926C126322002 @default.
• W2021002926 hasConceptScore W2021002926C129900496 @default.
• W2021002926 hasConceptScore W2021002926C134018914 @default.
• W2021002926 hasConceptScore W2021002926C14705128 @default.
• W2021002926 hasConceptScore W2021002926C178790620 @default.
• W2021002926 hasConceptScore W2021002926C181199279 @default.
• W2021002926 hasConceptScore W2021002926C185592680 @default.
• W2021002926 hasConceptScore W2021002926C24998067 @default.
• W2021002926 hasConceptScore W2021002926C2776685179 @default.
• W2021002926 hasConceptScore W2021002926C2776914184 @default.
• W2021002926 hasConceptScore W2021002926C2777318727 @default.
• W2021002926 hasConceptScore W2021002926C2778445172 @default.
• W2021002926 hasConceptScore W2021002926C2778996431 @default.
• W2021002926 hasConceptScore W2021002926C55493867 @default.
• W2021002926 hasConceptScore W2021002926C71924100 @default.
• W2021002926 hasIssue "4" @default.
• W2021002926 hasLocation W20210029261 @default.
• W2021002926 hasOpenAccess W2021002926 @default.
• W2021002926 hasPrimaryLocation W20210029261 @default.
• W2021002926 hasRelatedWork W1969091183 @default.
• W2021002926 hasRelatedWork W1984619393 @default.
• W2021002926 hasRelatedWork W2024716869 @default.
• W2021002926 hasRelatedWork W2034768996 @default.
• W2021002926 hasRelatedWork W2054992011 @default.
• W2021002926 hasRelatedWork W2060618991 @default.
• W2021002926 hasRelatedWork W2064416809 @default.

• next