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- W2021004793 abstract "Fourteen days after hippocampal microinfusion with colchicine (COL), learning and memory ability of mice was significantly impaired, while glutamate (Glu), γ-aminobutyric acid (GABA), Glu/GABA and GABAB receptor levels in the cortex and/or the hippocampus were significantly changed. After treatment with a GABAB receptor antagonist, CGP36742, learning and memory impairment caused by COL could be significantly improved, and the above indices in brain regions reversed. These results suggest GABAB antagonists may have therapeutic value in the treatment of Alzheimer's disease. ©1997 Elsevier Science B.V. All rights reserved." @default.
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- W2021004793 date "1997-03-01" @default.
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- W2021004793 title "Mechanism of colchicine impairment on learning and memory, and protective effect of CGP36742 in mice" @default.
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- W2021004793 doi "https://doi.org/10.1016/s0006-8993(96)01158-4" @default.
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