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• W2021011397 abstract "Abstract The Cu(II) complexes of type [Cu(cpf)(A n )Cl] (A n = terpyridines, cpf = ciprofloxacin) were synthesized and characterized using IR, mass and reflectance spectra. The free ligands and their complexes were evaluated for their in‐vitro antimicrobial activity against a panel of Gram‐positive and Gram‐negative bacteria. The complexes exhibit better or equal inhibition in comparison to free fluoroquinolones. Binding interactions of the complexes with calf thymus (CT DNA) were investigated by absorption titration, viscosity studies and DNA melting temperature experiment. The cleavage reaction on pUC19 DNA was monitored by agarose gel electrophoresis. The lower concentration of the complexes was catalysed the dismutation of superoxide radical at biological pH, which indicates that the complexes can act as a possible model for superoxide dismutase. Copyright © 2011 John Wiley & Sons, Ltd." @default.
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• W2021011397 date "2011-08-10" @default.
• W2021011397 modified "2023-10-16" @default.
• W2021011397 title "DNA interaction, free radical scavenging and in-vitro antibacterial activity of drug-based copper(II) complexes" @default.
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• W2021011397 doi "https://doi.org/10.1002/aoc.1817" @default.
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