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- W2021013207 abstract "The cell surface expression of receptors for TGF-beta was studied in human osteoblasts derived from femoral trabecular bone of a total of 19 patients aged 2-83 years. All cell populations investigated showed a similar profile of expression of TGF-beta receptors (TbetaR) I, II and III (betaglycan). There were no significant differences in cell differentiation or proliferative behaviour between the age groups. The TGF-beta receptor number per cell significantly increased with age, while the receptor affinity tended to decrease. IGF-I did not influence TbetaR expression in vitro. The results indicate an age-dependent and IGF-I independent increase of osteoblastic TGF-beta receptors in human osteoblast-like cells in vitro." @default.
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- W2021013207 date "2000-12-31" @default.
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- W2021013207 title "Age-related differences in the expression of receptors for TGF-<i>β</i> in human osteoblast-like cells in vitro" @default.
- W2021013207 doi "https://doi.org/10.1055/s-2000-8001" @default.
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