Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021013463> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2021013463 abstract "The introduction of first-generation protease inhibitors for the treatment of chronic hepatitis C in subjects infected with hepatitis C virus (HCV) genotype 1 has significantly improved the sustained virological response (SVR) rate. As liver cirrhosis reduces the probability of achieving SVR, current guidelines discourage response-guided therapy in cirrhotic patients. We report the first case of a cirrhotic woman with chronic HCV and HIV co-infection achieving virological response after an ultra-short course of therapy. A 40-year-old HIV/HCV co-infected woman with compensated liver cirrhosis was treated with anti-HCV triple therapy containing telaprevir plus pegylated interferon and ribavirin. Baseline plasma HCV RNA was 3.6 log IU/ml and transaminases were within the normal range. She harboured IL28B rs12979860C/C alleles. Ten days after starting therapy, the patient stopped treatment because of mild anorexia and nausea. Virological response was detected at treatment discontinuation and was maintained up to 24 weeks. This case describes an unexpected SVR after a 10-day course of antiviral therapy in a cirrhotic HIV/HCV co-infected woman presenting positive predictive factors for a response (low viral load, IL28B genotype). Nonetheless, there is no evidence to suggest a shorter duration of treatment in this subset of patients." @default.
- W2021013463 created "2016-06-24" @default.
- W2021013463 creator A5021984756 @default.
- W2021013463 creator A5027178314 @default.
- W2021013463 creator A5042178795 @default.
- W2021013463 creator A5047570485 @default.
- W2021013463 creator A5059418390 @default.
- W2021013463 creator A5075116620 @default.
- W2021013463 creator A5081071409 @default.
- W2021013463 creator A5085955080 @default.
- W2021013463 date "2014-12-01" @default.
- W2021013463 modified "2023-09-23" @default.
- W2021013463 title "Sustained virological response after ten days of triple anti-hepatitis C virus (HCV) therapy with telaprevir plus pegylated interferon and ribavirin in an HIV/HCV co-infected cirrhotic woman" @default.
- W2021013463 cites W1965358723 @default.
- W2021013463 cites W2049390811 @default.
- W2021013463 cites W2063964141 @default.
- W2021013463 cites W2334051783 @default.
- W2021013463 doi "https://doi.org/10.1016/j.ijid.2014.08.011" @default.
- W2021013463 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25449243" @default.
- W2021013463 hasPublicationYear "2014" @default.
- W2021013463 type Work @default.
- W2021013463 sameAs 2021013463 @default.
- W2021013463 citedByCount "2" @default.
- W2021013463 countsByYear W20210134632016 @default.
- W2021013463 countsByYear W20210134632018 @default.
- W2021013463 crossrefType "journal-article" @default.
- W2021013463 hasAuthorship W2021013463A5021984756 @default.
- W2021013463 hasAuthorship W2021013463A5027178314 @default.
- W2021013463 hasAuthorship W2021013463A5042178795 @default.
- W2021013463 hasAuthorship W2021013463A5047570485 @default.
- W2021013463 hasAuthorship W2021013463A5059418390 @default.
- W2021013463 hasAuthorship W2021013463A5075116620 @default.
- W2021013463 hasAuthorship W2021013463A5081071409 @default.
- W2021013463 hasAuthorship W2021013463A5085955080 @default.
- W2021013463 hasBestOaLocation W20210134631 @default.
- W2021013463 hasConcept C126322002 @default.
- W2021013463 hasConcept C142462285 @default.
- W2021013463 hasConcept C203014093 @default.
- W2021013463 hasConcept C2522874641 @default.
- W2021013463 hasConcept C2776408679 @default.
- W2021013463 hasConcept C2776455275 @default.
- W2021013463 hasConcept C2776461080 @default.
- W2021013463 hasConcept C2776999253 @default.
- W2021013463 hasConcept C2777214474 @default.
- W2021013463 hasConcept C2778159067 @default.
- W2021013463 hasConcept C2778715236 @default.
- W2021013463 hasConcept C2780040827 @default.
- W2021013463 hasConcept C71924100 @default.
- W2021013463 hasConcept C90924648 @default.
- W2021013463 hasConceptScore W2021013463C126322002 @default.
- W2021013463 hasConceptScore W2021013463C142462285 @default.
- W2021013463 hasConceptScore W2021013463C203014093 @default.
- W2021013463 hasConceptScore W2021013463C2522874641 @default.
- W2021013463 hasConceptScore W2021013463C2776408679 @default.
- W2021013463 hasConceptScore W2021013463C2776455275 @default.
- W2021013463 hasConceptScore W2021013463C2776461080 @default.
- W2021013463 hasConceptScore W2021013463C2776999253 @default.
- W2021013463 hasConceptScore W2021013463C2777214474 @default.
- W2021013463 hasConceptScore W2021013463C2778159067 @default.
- W2021013463 hasConceptScore W2021013463C2778715236 @default.
- W2021013463 hasConceptScore W2021013463C2780040827 @default.
- W2021013463 hasConceptScore W2021013463C71924100 @default.
- W2021013463 hasConceptScore W2021013463C90924648 @default.
- W2021013463 hasLocation W20210134631 @default.
- W2021013463 hasLocation W20210134632 @default.
- W2021013463 hasLocation W20210134633 @default.
- W2021013463 hasLocation W20210134634 @default.
- W2021013463 hasOpenAccess W2021013463 @default.
- W2021013463 hasPrimaryLocation W20210134631 @default.
- W2021013463 hasRelatedWork W1586232317 @default.
- W2021013463 hasRelatedWork W2021013463 @default.
- W2021013463 hasRelatedWork W2034228609 @default.
- W2021013463 hasRelatedWork W2060044480 @default.
- W2021013463 hasRelatedWork W2060441409 @default.
- W2021013463 hasRelatedWork W2089625154 @default.
- W2021013463 hasRelatedWork W2166034731 @default.
- W2021013463 hasRelatedWork W2358339988 @default.
- W2021013463 hasRelatedWork W2517087858 @default.
- W2021013463 hasRelatedWork W2755121454 @default.
- W2021013463 isParatext "false" @default.
- W2021013463 isRetracted "false" @default.
- W2021013463 magId "2021013463" @default.
- W2021013463 workType "article" @default.