Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021017308> ?p ?o ?g. }
- W2021017308 endingPage "389" @default.
- W2021017308 startingPage "381" @default.
- W2021017308 abstract "Chronic cannabis use has been associated with neurocognitive deficits, alterations in brain structure and function, and with psychosis. This study investigated the effects of chronic cannabis use on P50 sensory-gating in regular users, and explored the association between sensory gating, cannabis use history and the development of psychotic-like symptoms. Twenty controls and 21 regular cannabis users completed a P50 paired-click (S1 and S2) paradigm with an inter-pair interval of 9 s. The groups were compared on P50 amplitude to S1 and S2, P50 ratio (S2/S1) and P50 difference score (S1–S2). While cannabis users overall did not differ from controls on P50 measures, prolonged duration of regular use was associated with greater impairment in sensory gating as indexed by both P50 ratio and difference scores (including after controlling for tobacco use). Long-term cannabis users were found to have worse sensory gating ratios and difference scores compared to short-term users and controls. P50 metrics did not correlate significantly with any measure of psychotic-like symptoms in cannabis users. These results suggest that prolonged exposure to cannabis results in impaired P50 sensory-gating in long-term cannabis users. While it is possible that these deficits may have pre-dated cannabis use and reflect a vulnerability to cannabis use, their association with increasing years of cannabis use suggests that this is not the case. Impaired P50 sensory-gating ratios have also been reported in patients with schizophrenia and may indicate a similar underlying pathology." @default.
- W2021017308 created "2016-06-24" @default.
- W2021017308 creator A5000041995 @default.
- W2021017308 creator A5002095024 @default.
- W2021017308 creator A5027917089 @default.
- W2021017308 creator A5049430041 @default.
- W2021017308 creator A5056843030 @default.
- W2021017308 creator A5061764419 @default.
- W2021017308 creator A5063703477 @default.
- W2021017308 creator A5076980072 @default.
- W2021017308 date "2013-09-01" @default.
- W2021017308 modified "2023-10-16" @default.
- W2021017308 title "Chronic effects of cannabis on sensory gating" @default.
- W2021017308 cites W1662387941 @default.
- W2021017308 cites W1849383792 @default.
- W2021017308 cites W1967187196 @default.
- W2021017308 cites W1973661620 @default.
- W2021017308 cites W1975913434 @default.
- W2021017308 cites W1980680444 @default.
- W2021017308 cites W1980967004 @default.
- W2021017308 cites W1981703923 @default.
- W2021017308 cites W1984087539 @default.
- W2021017308 cites W1985748151 @default.
- W2021017308 cites W1991995213 @default.
- W2021017308 cites W1992434575 @default.
- W2021017308 cites W1992771452 @default.
- W2021017308 cites W1994037263 @default.
- W2021017308 cites W1997991955 @default.
- W2021017308 cites W2002178426 @default.
- W2021017308 cites W2005000985 @default.
- W2021017308 cites W2007497414 @default.
- W2021017308 cites W2012403108 @default.
- W2021017308 cites W2016957475 @default.
- W2021017308 cites W2024621431 @default.
- W2021017308 cites W2025961724 @default.
- W2021017308 cites W2030556473 @default.
- W2021017308 cites W2031130940 @default.
- W2021017308 cites W2040409456 @default.
- W2021017308 cites W2043989091 @default.
- W2021017308 cites W2044923137 @default.
- W2021017308 cites W2047903753 @default.
- W2021017308 cites W2052812707 @default.
- W2021017308 cites W2057552760 @default.
- W2021017308 cites W2059223813 @default.
- W2021017308 cites W2061510253 @default.
- W2021017308 cites W2069810132 @default.
- W2021017308 cites W2070142071 @default.
- W2021017308 cites W2070356484 @default.
- W2021017308 cites W2074080376 @default.
- W2021017308 cites W2080565837 @default.
- W2021017308 cites W2081617660 @default.
- W2021017308 cites W2082979163 @default.
- W2021017308 cites W2083540742 @default.
- W2021017308 cites W2084596338 @default.
- W2021017308 cites W2084679802 @default.
- W2021017308 cites W2091062477 @default.
- W2021017308 cites W2091606458 @default.
- W2021017308 cites W2094414770 @default.
- W2021017308 cites W2096833894 @default.
- W2021017308 cites W2097527558 @default.
- W2021017308 cites W2107131729 @default.
- W2021017308 cites W2107642085 @default.
- W2021017308 cites W2108913589 @default.
- W2021017308 cites W2110608362 @default.
- W2021017308 cites W2111123102 @default.
- W2021017308 cites W2116820689 @default.
- W2021017308 cites W2119369829 @default.
- W2021017308 cites W2121894737 @default.
- W2021017308 cites W2127931285 @default.
- W2021017308 cites W2129064912 @default.
- W2021017308 cites W2129378060 @default.
- W2021017308 cites W2132159513 @default.
- W2021017308 cites W2132218777 @default.
- W2021017308 cites W2132835664 @default.
- W2021017308 cites W2133976538 @default.
- W2021017308 cites W2136022845 @default.
- W2021017308 cites W2139228555 @default.
- W2021017308 cites W2143193334 @default.
- W2021017308 cites W2144366004 @default.
- W2021017308 cites W2147190696 @default.
- W2021017308 cites W2156705297 @default.
- W2021017308 cites W2159609705 @default.
- W2021017308 cites W2161298949 @default.
- W2021017308 cites W2165151662 @default.
- W2021017308 cites W2167703243 @default.
- W2021017308 cites W2168111104 @default.
- W2021017308 cites W2168327895 @default.
- W2021017308 cites W2395237642 @default.
- W2021017308 cites W2410784178 @default.
- W2021017308 doi "https://doi.org/10.1016/j.ijpsycho.2013.04.015" @default.
- W2021017308 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23628289" @default.
- W2021017308 hasPublicationYear "2013" @default.
- W2021017308 type Work @default.
- W2021017308 sameAs 2021017308 @default.
- W2021017308 citedByCount "27" @default.
- W2021017308 countsByYear W20210173082013 @default.
- W2021017308 countsByYear W20210173082014 @default.
- W2021017308 countsByYear W20210173082015 @default.