Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021019744> ?p ?o ?g. }
- W2021019744 endingPage "376" @default.
- W2021019744 startingPage "369" @default.
- W2021019744 abstract "Objective. To determine the outcome of Finnish children and adolescents with idiopathic dilated cardiomyopathy (IDCM) and factors that might be useful as prognostic indicators. Methodology. The clinical profile and course of 62 Finnish children and adolescents (median age, 13 months; range, 1 day to 20 years) with IDCM in 1980 to 1991 were evaluated to detect factors that might predict outcome. Factors studied included age, gender, family history, previous viral illness, and symptoms and signs at presentation. Furthermore, data on serial electrocardiographic, echocardiographic, and chest x-ray examinations, histologic findings, and treatments were analyzed. Results. During a mean (±SD) follow-up of 3.9 ± 4.5 years (range, 1 day to 25 years), 10 patients (16%) recovered, 17 (27%) had residual disease, 4 (6.4%) underwent heart transplantation, and 31 (50%) died. Infants (<1 year of age) and adolescent (≥15 years of age) male patients with progressing symptoms of left ventricular failure after initiation of medical therapy tended to have the poorest outcome. However, in multivariate analysis, only histologic evidence of endocardial fibroelastosis, clinical signs of right ventricular failure at presentation, and the need for anticoagulative therapy during follow-up, the last an expression of a severely impaired left ventricular systolic function, appeared to be significant predictors of long-term outcome. Conclusions. Our study confirms that the outcome of children with IDCM still remains poor. However, a group of patients, mainly infants, make a full recovery. Adolescent male patients as well as infants suffering from endocardial fibroelastosis with persisting symptoms of congestive heart failure after initiation of medical therapy tend to have the poorest outcome. These patients need a careful follow-up at short time intervals and, in the case of lacking response to medical treatment with resulting growth failure and/or poor quality of life, should be offered urgent heart transplantation." @default.
- W2021019744 created "2016-06-24" @default.
- W2021019744 creator A5006824790 @default.
- W2021019744 creator A5013461384 @default.
- W2021019744 creator A5043316180 @default.
- W2021019744 creator A5047301255 @default.
- W2021019744 date "1998-03-01" @default.
- W2021019744 modified "2023-10-17" @default.
- W2021019744 title "Idiopathic Dilated Cardiomyopathy in Children: Prognostic Indicators and Outcome" @default.
- W2021019744 cites W1489130191 @default.
- W2021019744 cites W1969866449 @default.
- W2021019744 cites W1976796709 @default.
- W2021019744 cites W1977127536 @default.
- W2021019744 cites W1986167000 @default.
- W2021019744 cites W1986409524 @default.
- W2021019744 cites W1991332142 @default.
- W2021019744 cites W1991768709 @default.
- W2021019744 cites W2002208962 @default.
- W2021019744 cites W2006555760 @default.
- W2021019744 cites W2010790997 @default.
- W2021019744 cites W2020780227 @default.
- W2021019744 cites W2034469825 @default.
- W2021019744 cites W2051133244 @default.
- W2021019744 cites W2053359234 @default.
- W2021019744 cites W2054603937 @default.
- W2021019744 cites W2060114255 @default.
- W2021019744 cites W2070709304 @default.
- W2021019744 cites W2074077186 @default.
- W2021019744 cites W2077553167 @default.
- W2021019744 cites W2079892147 @default.
- W2021019744 cites W2080694717 @default.
- W2021019744 cites W2081485152 @default.
- W2021019744 cites W2089090856 @default.
- W2021019744 cites W2091402984 @default.
- W2021019744 cites W2092135214 @default.
- W2021019744 cites W2094333636 @default.
- W2021019744 cites W2106473563 @default.
- W2021019744 cites W2144059284 @default.
- W2021019744 cites W2156200001 @default.
- W2021019744 cites W2159938367 @default.
- W2021019744 cites W2167356620 @default.
- W2021019744 cites W2313269561 @default.
- W2021019744 cites W2326160676 @default.
- W2021019744 cites W2329687194 @default.
- W2021019744 cites W58511014 @default.
- W2021019744 doi "https://doi.org/10.1542/peds.101.3.369" @default.
- W2021019744 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9480999" @default.
- W2021019744 hasPublicationYear "1998" @default.
- W2021019744 type Work @default.
- W2021019744 sameAs 2021019744 @default.
- W2021019744 citedByCount "138" @default.
- W2021019744 countsByYear W20210197442012 @default.
- W2021019744 countsByYear W20210197442013 @default.
- W2021019744 countsByYear W20210197442014 @default.
- W2021019744 countsByYear W20210197442015 @default.
- W2021019744 countsByYear W20210197442016 @default.
- W2021019744 countsByYear W20210197442017 @default.
- W2021019744 countsByYear W20210197442018 @default.
- W2021019744 countsByYear W20210197442019 @default.
- W2021019744 countsByYear W20210197442020 @default.
- W2021019744 countsByYear W20210197442021 @default.
- W2021019744 countsByYear W20210197442022 @default.
- W2021019744 countsByYear W20210197442023 @default.
- W2021019744 crossrefType "journal-article" @default.
- W2021019744 hasAuthorship W2021019744A5006824790 @default.
- W2021019744 hasAuthorship W2021019744A5013461384 @default.
- W2021019744 hasAuthorship W2021019744A5043316180 @default.
- W2021019744 hasAuthorship W2021019744A5047301255 @default.
- W2021019744 hasConcept C126322002 @default.
- W2021019744 hasConcept C164705383 @default.
- W2021019744 hasConcept C187212893 @default.
- W2021019744 hasConcept C2776383484 @default.
- W2021019744 hasConcept C2778198053 @default.
- W2021019744 hasConcept C2778797674 @default.
- W2021019744 hasConcept C2781278803 @default.
- W2021019744 hasConcept C71924100 @default.
- W2021019744 hasConceptScore W2021019744C126322002 @default.
- W2021019744 hasConceptScore W2021019744C164705383 @default.
- W2021019744 hasConceptScore W2021019744C187212893 @default.
- W2021019744 hasConceptScore W2021019744C2776383484 @default.
- W2021019744 hasConceptScore W2021019744C2778198053 @default.
- W2021019744 hasConceptScore W2021019744C2778797674 @default.
- W2021019744 hasConceptScore W2021019744C2781278803 @default.
- W2021019744 hasConceptScore W2021019744C71924100 @default.
- W2021019744 hasIssue "3" @default.
- W2021019744 hasLocation W20210197441 @default.
- W2021019744 hasLocation W20210197442 @default.
- W2021019744 hasOpenAccess W2021019744 @default.
- W2021019744 hasPrimaryLocation W20210197441 @default.
- W2021019744 hasRelatedWork W1567335236 @default.
- W2021019744 hasRelatedWork W2056293439 @default.
- W2021019744 hasRelatedWork W2060435028 @default.
- W2021019744 hasRelatedWork W2091247174 @default.
- W2021019744 hasRelatedWork W2106990917 @default.
- W2021019744 hasRelatedWork W2141745555 @default.
- W2021019744 hasRelatedWork W2152300618 @default.
- W2021019744 hasRelatedWork W2156053371 @default.
- W2021019744 hasRelatedWork W2405027122 @default.