SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021033923> ?p ?o ?g. }

Showing items 1 to 93 of 93 with 100 items per page.

W2021033923 endingPage "205" @default.
W2021033923 startingPage "205" @default.
W2021033923 abstract "Ten patients with low-renin hypertension were treated with high doses of a diuretic and a mineralocorticoid antagonist in a double-blind crossover study. Hydrochlorothiazide-induced volume depletion had a beneficial hypotensive response. However, despite comparable diuretic response, the hypotensive response observed with spironolactone was significantly greater. Renin responsiveness was seen to increase—but to submaximal levels—with thiazide therapy; while spironolactone therapy restored normal renin responsiveness. The differential response to thiazide and spironolactone is similar to the response observed when these agents are used in primary aldosteronism, a hypertensive disease where mineralocorticoid excess is clearly identified as the cause of both the hypertension and low plasma renin activity. The fact that mineralocorticoid blockade induced by spironolactone corrects the hypertension and restores normal renin responsiveness suggests that mineralocorticoid excess may be responsible for the hypertension and low plasma renin activity." @default.
W2021033923 created "2016-06-24" @default.
W2021033923 creator A5004453202 @default.
W2021033923 creator A5084828767 @default.
W2021033923 creator A5089993010 @default.
W2021033923 date "1974-02-01" @default.
W2021033923 modified "2023-09-25" @default.
W2021033923 title "Low-Renin Hypertension" @default.
W2021033923 cites W1975622210 @default.
W2021033923 cites W1981030543 @default.
W2021033923 cites W1997388963 @default.
W2021033923 cites W1998433899 @default.
W2021033923 cites W2001487652 @default.
W2021033923 cites W2005739758 @default.
W2021033923 cites W2012583578 @default.
W2021033923 cites W2017666632 @default.
W2021033923 cites W2019645953 @default.
W2021033923 cites W2025063380 @default.
W2021033923 cites W2031051250 @default.
W2021033923 cites W2031135412 @default.
W2021033923 cites W2039969582 @default.
W2021033923 cites W2041647493 @default.
W2021033923 cites W2081923456 @default.
W2021033923 cites W2108137018 @default.
W2021033923 cites W2117150574 @default.
W2021033923 cites W2122595081 @default.
W2021033923 cites W2133122846 @default.
W2021033923 cites W2144310145 @default.
W2021033923 cites W2342067247 @default.
W2021033923 cites W2399069406 @default.
W2021033923 cites W1990209083 @default.
W2021033923 doi "https://doi.org/10.1001/archinte.1974.00320140043004" @default.
W2021033923 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4591266" @default.
W2021033923 hasPublicationYear "1974" @default.
W2021033923 type Work @default.
W2021033923 sameAs 2021033923 @default.
W2021033923 citedByCount "30" @default.
W2021033923 crossrefType "journal-article" @default.
W2021033923 hasAuthorship W2021033923A5004453202 @default.
W2021033923 hasAuthorship W2021033923A5084828767 @default.
W2021033923 hasAuthorship W2021033923A5089993010 @default.
W2021033923 hasConcept C126322002 @default.
W2021033923 hasConcept C134018914 @default.
W2021033923 hasConcept C138976137 @default.
W2021033923 hasConcept C189135053 @default.
W2021033923 hasConcept C198710026 @default.
W2021033923 hasConcept C2776069600 @default.
W2021033923 hasConcept C2776379505 @default.
W2021033923 hasConcept C2777097880 @default.
W2021033923 hasConcept C2777955127 @default.
W2021033923 hasConcept C2778525890 @default.
W2021033923 hasConcept C2779918671 @default.
W2021033923 hasConcept C2780361556 @default.
W2021033923 hasConcept C2780437262 @default.
W2021033923 hasConcept C71924100 @default.
W2021033923 hasConcept C84393581 @default.
W2021033923 hasConceptScore W2021033923C126322002 @default.
W2021033923 hasConceptScore W2021033923C134018914 @default.
W2021033923 hasConceptScore W2021033923C138976137 @default.
W2021033923 hasConceptScore W2021033923C189135053 @default.
W2021033923 hasConceptScore W2021033923C198710026 @default.
W2021033923 hasConceptScore W2021033923C2776069600 @default.
W2021033923 hasConceptScore W2021033923C2776379505 @default.
W2021033923 hasConceptScore W2021033923C2777097880 @default.
W2021033923 hasConceptScore W2021033923C2777955127 @default.
W2021033923 hasConceptScore W2021033923C2778525890 @default.
W2021033923 hasConceptScore W2021033923C2779918671 @default.
W2021033923 hasConceptScore W2021033923C2780361556 @default.
W2021033923 hasConceptScore W2021033923C2780437262 @default.
W2021033923 hasConceptScore W2021033923C71924100 @default.
W2021033923 hasConceptScore W2021033923C84393581 @default.
W2021033923 hasIssue "2" @default.
W2021033923 hasLocation W20210339231 @default.
W2021033923 hasLocation W20210339232 @default.
W2021033923 hasOpenAccess W2021033923 @default.
W2021033923 hasPrimaryLocation W20210339231 @default.
W2021033923 hasRelatedWork W174527792 @default.
W2021033923 hasRelatedWork W177169742 @default.
W2021033923 hasRelatedWork W1976795475 @default.
W2021033923 hasRelatedWork W2021033923 @default.
W2021033923 hasRelatedWork W2037408526 @default.
W2021033923 hasRelatedWork W2105380188 @default.
W2021033923 hasRelatedWork W2312942238 @default.
W2021033923 hasRelatedWork W2322243425 @default.
W2021033923 hasRelatedWork W2589899659 @default.
W2021033923 hasRelatedWork W4232426836 @default.
W2021033923 hasVolume "133" @default.
W2021033923 isParatext "false" @default.
W2021033923 isRetracted "false" @default.
W2021033923 magId "2021033923" @default.
W2021033923 workType "article" @default.