Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021034240> ?p ?o ?g. }
- W2021034240 endingPage "330" @default.
- W2021034240 startingPage "319" @default.
- W2021034240 abstract "Abstract Podocytes are postmitotic renal glomerular cells with multiple ramifications that extend from the cell body. Processes departing from a podocyte interdigitate with corresponding projections from neighboring cells and form an intricate web that enwraps the glomerular capillary completely. Podocyte processes are interconnected by the slit diaphragm, an adhesion junction mostly formed by Ig-like molecules, cadherins/protocadherins, ephrin/eph, and neurexin molecules organized in an assembly that resembles synaptic junctions. Podocyte failure is primarily or secondarily implicated in all forms of proteinuric glomerular diseases, as confirmed by the morphological changes of their elaborate cell architecture detectable by electron microscopy. Importantly, mutations of podocyte proteins are responsible for the most severe forms of congenital nephrotic syndrome. In the last 15 years, progressive technological advances have aided the study of podocyte biology and pathology, confirming the relevance of podocyte molecules and signaling pathways for the function of the glomerular filter. This review will examine the most important and newest discoveries in the field, which is rapidly evolving, hopefully leading to a detailed knowledge of this fascinating cell and to the development of specific therapeutic options for proteinuric diseases." @default.
- W2021034240 created "2016-06-24" @default.
- W2021034240 creator A5004804603 @default.
- W2021034240 creator A5011863838 @default.
- W2021034240 creator A5014970553 @default.
- W2021034240 creator A5025876675 @default.
- W2021034240 creator A5026530346 @default.
- W2021034240 creator A5037151999 @default.
- W2021034240 creator A5064594935 @default.
- W2021034240 creator A5066042051 @default.
- W2021034240 creator A5066785571 @default.
- W2021034240 creator A5070949543 @default.
- W2021034240 date "2014-08-01" @default.
- W2021034240 modified "2023-09-27" @default.
- W2021034240 title "Podocytes: recent biomolecular developments" @default.
- W2021034240 cites W1557400022 @default.
- W2021034240 cites W1967471692 @default.
- W2021034240 cites W1970749484 @default.
- W2021034240 cites W1977220329 @default.
- W2021034240 cites W1987294439 @default.
- W2021034240 cites W1998554604 @default.
- W2021034240 cites W2003736068 @default.
- W2021034240 cites W2011544204 @default.
- W2021034240 cites W2013239609 @default.
- W2021034240 cites W2018643157 @default.
- W2021034240 cites W2040670636 @default.
- W2021034240 cites W2047649857 @default.
- W2021034240 cites W2054225562 @default.
- W2021034240 cites W2059946666 @default.
- W2021034240 cites W2082560177 @default.
- W2021034240 cites W2083063047 @default.
- W2021034240 cites W2086396348 @default.
- W2021034240 cites W2096672118 @default.
- W2021034240 cites W2097942434 @default.
- W2021034240 cites W2101975128 @default.
- W2021034240 cites W2106471679 @default.
- W2021034240 cites W2110701772 @default.
- W2021034240 cites W2115764731 @default.
- W2021034240 cites W2118491944 @default.
- W2021034240 cites W2121822730 @default.
- W2021034240 cites W2129037338 @default.
- W2021034240 cites W2133621860 @default.
- W2021034240 cites W2136921414 @default.
- W2021034240 cites W2137467666 @default.
- W2021034240 cites W2138329309 @default.
- W2021034240 cites W2145865611 @default.
- W2021034240 cites W2146098038 @default.
- W2021034240 cites W2148617543 @default.
- W2021034240 cites W2153534186 @default.
- W2021034240 cites W2154261062 @default.
- W2021034240 cites W2155641483 @default.
- W2021034240 cites W2160944895 @default.
- W2021034240 cites W2168539681 @default.
- W2021034240 doi "https://doi.org/10.1515/bmc-2014-0020" @default.
- W2021034240 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25372762" @default.
- W2021034240 hasPublicationYear "2014" @default.
- W2021034240 type Work @default.
- W2021034240 sameAs 2021034240 @default.
- W2021034240 citedByCount "17" @default.
- W2021034240 countsByYear W20210342402016 @default.
- W2021034240 countsByYear W20210342402018 @default.
- W2021034240 countsByYear W20210342402019 @default.
- W2021034240 countsByYear W20210342402020 @default.
- W2021034240 countsByYear W20210342402021 @default.
- W2021034240 countsByYear W20210342402022 @default.
- W2021034240 crossrefType "journal-article" @default.
- W2021034240 hasAuthorship W2021034240A5004804603 @default.
- W2021034240 hasAuthorship W2021034240A5011863838 @default.
- W2021034240 hasAuthorship W2021034240A5014970553 @default.
- W2021034240 hasAuthorship W2021034240A5025876675 @default.
- W2021034240 hasAuthorship W2021034240A5026530346 @default.
- W2021034240 hasAuthorship W2021034240A5037151999 @default.
- W2021034240 hasAuthorship W2021034240A5064594935 @default.
- W2021034240 hasAuthorship W2021034240A5066042051 @default.
- W2021034240 hasAuthorship W2021034240A5066785571 @default.
- W2021034240 hasAuthorship W2021034240A5070949543 @default.
- W2021034240 hasBestOaLocation W20210342401 @default.
- W2021034240 hasConcept C101544691 @default.
- W2021034240 hasConcept C1491633281 @default.
- W2021034240 hasConcept C149402561 @default.
- W2021034240 hasConcept C16224149 @default.
- W2021034240 hasConcept C169760540 @default.
- W2021034240 hasConcept C170286479 @default.
- W2021034240 hasConcept C170493617 @default.
- W2021034240 hasConcept C19331615 @default.
- W2021034240 hasConcept C197341189 @default.
- W2021034240 hasConcept C2777146197 @default.
- W2021034240 hasConcept C2778162979 @default.
- W2021034240 hasConcept C2779561371 @default.
- W2021034240 hasConcept C2780091579 @default.
- W2021034240 hasConcept C2780819817 @default.
- W2021034240 hasConcept C3018201436 @default.
- W2021034240 hasConcept C54355233 @default.
- W2021034240 hasConcept C62478195 @default.
- W2021034240 hasConcept C86803240 @default.
- W2021034240 hasConcept C95444343 @default.
- W2021034240 hasConceptScore W2021034240C101544691 @default.
- W2021034240 hasConceptScore W2021034240C1491633281 @default.