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- W2021046120 abstract "c-Fos is a nuclear phosphoprotein coded by the proto-oncogen c-fos which can be detected immunohistochemically after both physiological and pathological stimuli. This property is of great importance, because it offers a valuable tool for morphofunctional identification of activated neurons. We have studied the neuronal activity in the visual pathway of Tupaia belangeri within the following anatomical structures: retina, superior colliculus (SC), dorsal lateral geniculate nucleus (dLGN), pulvinar (Pu), parabigeminal (PBG) nucleus and primary visual cortex (V1) analyzing the c-Fos expression after exposing the tree shrews to different light stimuli (white light -control positive group-, green light, blue light and darkness conditions -control negative group-). Our findings suggest that in the retina, the ganglion cells and the cells of the inner nuclear layer respond better to blue and green light stimuli, when comparing the c-Fos expression between white, green, blue lights and darkness conditions. However, in the SC, dLGN, Pu, PBG nucleus and V1 another pattern of c-Fos expression is observed: a maximum expression for the control positive group, a minimum expression for the control negative group and intermediate expressions within the blue and green light groups.the expression levels of c-Fos protein are able to show significant differences between distinct light stimuli in all anatomical structures studied (retina, SC, dLGN, Pu, PBG and V1) of T. belangeri." @default.
- W2021046120 created "2016-06-24" @default.
- W2021046120 creator A5064345316 @default.
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- W2021046120 date "2009-07-01" @default.
- W2021046120 modified "2023-10-16" @default.
- W2021046120 title "c-Fos expression in the visual system of the tree shrew (Tupaia belangeri)" @default.
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- W2021046120 doi "https://doi.org/10.1016/j.jchemneu.2009.03.006" @default.
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