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- W2021052557 abstract "The active sequence Phe7-D-Trp8-Lys9-Thr10 of somatostatin has been cyclized through o-(aminomethyl)phenylacetic acid, a spacer molecule, designed to mimic a Gly-Gly dipeptide containing a cis-constrained peptide bond. The resulting analogue shows no GH-inhibition. A 2D n.m.r. study reveals conformations different from the proposed bio-active one and still sensitive to the medium (solvent)." @default.
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- W2021052557 date "2009-01-12" @default.
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- W2021052557 title "Synthesis and conformational study of a cyclic hexapeptide analogue of somatostatin: cyclo(Phe-D-Trp-Lys-Thr-o-AMPA)" @default.
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- W2021052557 doi "https://doi.org/10.1111/j.1399-3011.1987.tb02259.x" @default.
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