Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021065129> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2021065129 endingPage "1398" @default.
- W2021065129 startingPage "1381" @default.
- W2021065129 abstract "The following findings were obtained which bear on the mechanisms concerned in the rise of plasma free 17-hydroxycorticoid (17-OHCS) levels in patients treated with estrogenic hormone (ethinyl estradiol or diethylstilbestrol): 1) Cortisol accounted for approximately 80 per cent of the plasma free 17-OHCS in a normal subject given estrogen. 2) In patients treated with estrogenic hormone there was a marked rise in the level of plasma free 17-OHCS but no increase in urinary total 17-OHCS excretion. 3) In a man with intact adrenals who received ACTH intravenously and in an Addisonian woman who received cortisol intravenously there was a greater rise in the level of plasma free 17-OHCS and urinary F + E but a lesser rise in urinary THF+THE when estrogen was also administered. 4) On three occasions when patients with adrenal insufficiency were given cortisol intravenously, estrogen produced a diminished rate of removal of free 17-OHCS from plasma and a smaller distribution volume of the injected F. 5) The pituitary glands of 3 patients who had been receiving long-term estrogen therapy showed no Crooke's changes in the basophil cells. It is concluded that the rise in the level of plasma cortisol in patients receiving estrogen is due mainly to a diminished transformation of compound F to certain metabolites and to a greater retention of the hormone within the intravascular or possibly the extracellular fluid compartment. The failure of patients treated with estrogens to show evidence of an excess of cortisol is believed to be due in part to a failure of tissue levels of F to rise to the same degree as the plasma level of the hormone." @default.
- W2021065129 created "2016-06-24" @default.
- W2021065129 creator A5011211554 @default.
- W2021065129 creator A5017183352 @default.
- W2021065129 creator A5020319203 @default.
- W2021065129 date "1959-11-01" @default.
- W2021065129 modified "2023-10-16" @default.
- W2021065129 title "THE INFLUENCE OF ESTROGEN ON THE SECRETION, DISPOSITION AND BIOLOGIC ACTIVITY OF CORTISOL*" @default.
- W2021065129 cites W1522922542 @default.
- W2021065129 cites W1564759903 @default.
- W2021065129 cites W1972320107 @default.
- W2021065129 cites W2016551035 @default.
- W2021065129 cites W2019164791 @default.
- W2021065129 cites W2026475842 @default.
- W2021065129 cites W2028139743 @default.
- W2021065129 cites W2045582164 @default.
- W2021065129 cites W2062666273 @default.
- W2021065129 cites W2071459142 @default.
- W2021065129 cites W2072490666 @default.
- W2021065129 cites W2147898106 @default.
- W2021065129 cites W2171210829 @default.
- W2021065129 cites W2316521775 @default.
- W2021065129 cites W2334846637 @default.
- W2021065129 cites W3022655928 @default.
- W2021065129 cites W958047043 @default.
- W2021065129 cites W977330978 @default.
- W2021065129 doi "https://doi.org/10.1210/jcem-19-11-1381" @default.
- W2021065129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14437874" @default.
- W2021065129 hasPublicationYear "1959" @default.
- W2021065129 type Work @default.
- W2021065129 sameAs 2021065129 @default.
- W2021065129 citedByCount "39" @default.
- W2021065129 crossrefType "journal-article" @default.
- W2021065129 hasAuthorship W2021065129A5011211554 @default.
- W2021065129 hasAuthorship W2021065129A5017183352 @default.
- W2021065129 hasAuthorship W2021065129A5020319203 @default.
- W2021065129 hasConcept C10146269 @default.
- W2021065129 hasConcept C126322002 @default.
- W2021065129 hasConcept C134018914 @default.
- W2021065129 hasConcept C2777164284 @default.
- W2021065129 hasConcept C2778709874 @default.
- W2021065129 hasConcept C2781397067 @default.
- W2021065129 hasConcept C71315377 @default.
- W2021065129 hasConcept C71924100 @default.
- W2021065129 hasConcept C77411442 @default.
- W2021065129 hasConceptScore W2021065129C10146269 @default.
- W2021065129 hasConceptScore W2021065129C126322002 @default.
- W2021065129 hasConceptScore W2021065129C134018914 @default.
- W2021065129 hasConceptScore W2021065129C2777164284 @default.
- W2021065129 hasConceptScore W2021065129C2778709874 @default.
- W2021065129 hasConceptScore W2021065129C2781397067 @default.
- W2021065129 hasConceptScore W2021065129C71315377 @default.
- W2021065129 hasConceptScore W2021065129C71924100 @default.
- W2021065129 hasConceptScore W2021065129C77411442 @default.
- W2021065129 hasIssue "11" @default.
- W2021065129 hasLocation W20210651291 @default.
- W2021065129 hasLocation W20210651292 @default.
- W2021065129 hasOpenAccess W2021065129 @default.
- W2021065129 hasPrimaryLocation W20210651291 @default.
- W2021065129 hasRelatedWork W1963710704 @default.
- W2021065129 hasRelatedWork W1995647897 @default.
- W2021065129 hasRelatedWork W2013481652 @default.
- W2021065129 hasRelatedWork W2018087789 @default.
- W2021065129 hasRelatedWork W2027180407 @default.
- W2021065129 hasRelatedWork W2101821182 @default.
- W2021065129 hasRelatedWork W2109882125 @default.
- W2021065129 hasRelatedWork W2154101925 @default.
- W2021065129 hasRelatedWork W2168803779 @default.
- W2021065129 hasRelatedWork W4232275671 @default.
- W2021065129 hasVolume "19" @default.
- W2021065129 isParatext "false" @default.
- W2021065129 isRetracted "false" @default.
- W2021065129 magId "2021065129" @default.
- W2021065129 workType "article" @default.