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• W2021085391 abstract "NOC, NOC! Who's there? We have expanded the body of structure–activity relationships (SAR) regarding the 3-isoxazolecarboxylic acid ethyl esters by the design and synthesis of 5-aryl- and 5-[(N-aryl)amino]methyl analogues. Compounds were active against Mycobacterium tuberculosis (Mtb) at sub-micromolar concentrations and, for selected compounds, no toxicity was observed on Vero cells. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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• W2021085391 date "2010-08-18" @default.
• W2021085391 modified "2023-10-10" @default.
• W2021085391 title "NOC Chemistry for Tuberculosis-Further Investigations on the Structure-Activity Relationships of Antitubercular Isoxazole-3-carboxylic Acid Ester Derivatives" @default.
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• W2021085391 doi "https://doi.org/10.1002/cmdc.201000169" @default.
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