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• W2021094575 abstract "An 82-year-old woman had a dark red to purple tumor on the left buttock that had gradually enlarged during the last 5 years. Although routine histologic examination was not sufficient for diagnosis, neuroendocrine carcinoma was diagnosed by immunohistochemical and ultra-structural studies. Immunohistochemical-positive reactions to neurofilament, cytokeratin, neuron-specific enolase, and epithelial membrane antigen were noted. Electron microscopically, membrane-bound, dense core granules that yielded a positive uranaffin reaction and intermediate filaments in the perinuclear area were observed in the cytoplasm of most tumor cells. Desmosome-like structure between them was also found. Approximately 6 months after local excision, metastatic lesions developed in the regional lymph nodes and liver." @default.
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• W2021094575 date "1991-05-01" @default.
• W2021094575 modified "2023-09-27" @default.
• W2021094575 title "Giant neuroendocrine (Merkel cell) carcinoma of the skin" @default.
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• W2021094575 doi "https://doi.org/10.1016/0190-9622(91)70125-l" @default.
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