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- W2021103591 abstract "Mouse monoclonal antibodies, directed against antigenic sites on influenza A and B viruses and found to be type-specific in an immunoassay, were assessed for use as diagnostic reagents in an indirect immunofluorescence assay on nasopharyngeal secretions. The influenza A antibodies were directed against nucleoprotein or matrix protein antigens and the influenza B antibodies against nucleoprotein and haemagglutinin antigens. The influenza A anti-matrix monoclonal antibody was found to give a strong intranuclear particulate fluorescence in normal baboon kidney cells and cells from nasopharyngeal secretions negative for influenza A virus, including those from a patient infected with respiratory syncytial virus. Pools of the remaining monoclonal antibodies gave satisfactory results on 25 specimens from patients with influenza A H1N1 and H3N2 subtypes and 12 from patients with influenza B." @default.
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- W2021103591 date "1985-10-01" @default.
- W2021103591 modified "2023-09-27" @default.
- W2021103591 title "MONOCLONAL ANTIBODIES FOR THE RAPID DIAGNOSIS OF INFLUENZA A AND B VIRUS INFECTIONS BY IMMUNOFLUORESCENCE" @default.
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- W2021103591 doi "https://doi.org/10.1016/s0140-6736(85)90849-9" @default.
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