Matches in SemOpenAlex for { <https://semopenalex.org/work/W2021105938> ?p ?o ?g. }
- W2021105938 endingPage "548" @default.
- W2021105938 startingPage "544" @default.
- W2021105938 abstract "The mitral valve annulus has a distinctive saddle shape. Recent finite element analysis indicates this shape may contribute to normal valve function by increasing leaflet curvature and reducing leaflet stress. This study tests the hypothesis that acute ischemic mitral regurgitation (AIMR) is associated with loss of annular saddle shape.Sonomicrometry array localization (SAL) measured the three-dimensional geometry of the mitral annulus in 6 sheep before and after 30 min of posterior ischemia that produced severe AIMR. Using this SAL data the annular height to commissural width ratio (AHCWR), a measure of annular saddle shape, was calculated throughout the cardiac cycle and reported as a percentage.The normal mitral annulus accentuated its saddle shape rapidly during isovolemic contraction: AHCWR increased from 11.6% +/- 1.1%-13.9% +/- 1.6% (p < 0.001). During ejection AHCWR remained relatively constant ranging from a minimum of 14.1% +/- 1.5% to a maximum of 14.9% +/- 1.3%. During ischemia AHCWR was found to be significantly smaller (p < 0.05) during isovolemic contraction, ejection, and isovolemic relaxation, but not during diastolic filling. Whereas ischemia did not affect AHCWR at end diastole (11.6% +/- 2.8%), the isovolemic accentuation of the saddle shape was lost.The normal mitral annulus accentuates its saddle shape during systole. This accentuation is eliminated during ischemia that causes AIMR. These data suggest an association between annular saddle shape and valve competency." @default.
- W2021105938 created "2016-06-24" @default.
- W2021105938 creator A5018151758 @default.
- W2021105938 creator A5025599829 @default.
- W2021105938 creator A5045076711 @default.
- W2021105938 creator A5067583799 @default.
- W2021105938 date "2004-02-01" @default.
- W2021105938 modified "2023-09-23" @default.
- W2021105938 title "The effect of regional ischemia on mitral valve annular saddle shape" @default.
- W2021105938 cites W1941338328 @default.
- W2021105938 cites W1974787130 @default.
- W2021105938 cites W1976269561 @default.
- W2021105938 cites W1978542105 @default.
- W2021105938 cites W1986185736 @default.
- W2021105938 cites W2003596642 @default.
- W2021105938 cites W2008924366 @default.
- W2021105938 cites W2012948722 @default.
- W2021105938 cites W2027040058 @default.
- W2021105938 cites W2030042551 @default.
- W2021105938 cites W2031607557 @default.
- W2021105938 cites W2049626582 @default.
- W2021105938 cites W2061348777 @default.
- W2021105938 cites W2062448556 @default.
- W2021105938 cites W2114853973 @default.
- W2021105938 cites W2127150185 @default.
- W2021105938 cites W2132567621 @default.
- W2021105938 cites W2191399290 @default.
- W2021105938 cites W2520465500 @default.
- W2021105938 cites W4237177705 @default.
- W2021105938 cites W4244872663 @default.
- W2021105938 doi "https://doi.org/10.1016/s0003-4975(03)01354-7" @default.
- W2021105938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14759435" @default.
- W2021105938 hasPublicationYear "2004" @default.
- W2021105938 type Work @default.
- W2021105938 sameAs 2021105938 @default.
- W2021105938 citedByCount "93" @default.
- W2021105938 countsByYear W20211059382012 @default.
- W2021105938 countsByYear W20211059382013 @default.
- W2021105938 countsByYear W20211059382014 @default.
- W2021105938 countsByYear W20211059382015 @default.
- W2021105938 countsByYear W20211059382016 @default.
- W2021105938 countsByYear W20211059382017 @default.
- W2021105938 countsByYear W20211059382018 @default.
- W2021105938 countsByYear W20211059382021 @default.
- W2021105938 countsByYear W20211059382022 @default.
- W2021105938 crossrefType "journal-article" @default.
- W2021105938 hasAuthorship W2021105938A5018151758 @default.
- W2021105938 hasAuthorship W2021105938A5025599829 @default.
- W2021105938 hasAuthorship W2021105938A5045076711 @default.
- W2021105938 hasAuthorship W2021105938A5067583799 @default.
- W2021105938 hasConcept C105702510 @default.
- W2021105938 hasConcept C126255220 @default.
- W2021105938 hasConcept C126322002 @default.
- W2021105938 hasConcept C150936888 @default.
- W2021105938 hasConcept C159985019 @default.
- W2021105938 hasConcept C164705383 @default.
- W2021105938 hasConcept C169554166 @default.
- W2021105938 hasConcept C192562407 @default.
- W2021105938 hasConcept C2775938633 @default.
- W2021105938 hasConcept C2777127463 @default.
- W2021105938 hasConcept C2777543888 @default.
- W2021105938 hasConcept C2993373945 @default.
- W2021105938 hasConcept C33923547 @default.
- W2021105938 hasConcept C541997718 @default.
- W2021105938 hasConcept C57900726 @default.
- W2021105938 hasConcept C71924100 @default.
- W2021105938 hasConcept C84393581 @default.
- W2021105938 hasConcept C99398487 @default.
- W2021105938 hasConceptScore W2021105938C105702510 @default.
- W2021105938 hasConceptScore W2021105938C126255220 @default.
- W2021105938 hasConceptScore W2021105938C126322002 @default.
- W2021105938 hasConceptScore W2021105938C150936888 @default.
- W2021105938 hasConceptScore W2021105938C159985019 @default.
- W2021105938 hasConceptScore W2021105938C164705383 @default.
- W2021105938 hasConceptScore W2021105938C169554166 @default.
- W2021105938 hasConceptScore W2021105938C192562407 @default.
- W2021105938 hasConceptScore W2021105938C2775938633 @default.
- W2021105938 hasConceptScore W2021105938C2777127463 @default.
- W2021105938 hasConceptScore W2021105938C2777543888 @default.
- W2021105938 hasConceptScore W2021105938C2993373945 @default.
- W2021105938 hasConceptScore W2021105938C33923547 @default.
- W2021105938 hasConceptScore W2021105938C541997718 @default.
- W2021105938 hasConceptScore W2021105938C57900726 @default.
- W2021105938 hasConceptScore W2021105938C71924100 @default.
- W2021105938 hasConceptScore W2021105938C84393581 @default.
- W2021105938 hasConceptScore W2021105938C99398487 @default.
- W2021105938 hasIssue "2" @default.
- W2021105938 hasLocation W20211059381 @default.
- W2021105938 hasLocation W20211059382 @default.
- W2021105938 hasOpenAccess W2021105938 @default.
- W2021105938 hasPrimaryLocation W20211059381 @default.
- W2021105938 hasRelatedWork W1976164783 @default.
- W2021105938 hasRelatedWork W1981093874 @default.
- W2021105938 hasRelatedWork W2077848857 @default.
- W2021105938 hasRelatedWork W2091330059 @default.
- W2021105938 hasRelatedWork W2114853973 @default.
- W2021105938 hasRelatedWork W2270584142 @default.
- W2021105938 hasRelatedWork W2409600166 @default.