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• W2021106064 abstract "The effects of a carbohydrate-based diet (50% carbohydrate calories, 30% fat calories, 20% protein calories) versus a fat-based diet (28% carbohydrate calories, 55% fat calories, 17% protein calories) on oxidation rates of carbohydrate, fat, and protein were assessed in 12 patients with infections by indirect calorimetry and estimation of urea nitrogen production rate. The diets were given continuously for 18 hours in a randomized cross-over study on 2 consecutive days. Energy supply (kcal/d) was adjusted individually to meet the energy expenditure measured on the preceding day after an overnight fast and was 1,647 ± 129 (SEM) for the carbohydrate-based diet and 1,655 ± 131 for the fat-based diet. Oxidation rates (kcal/d) for carbohydrate (carbohydrate-based diet, 525 ± 70; fat-based diet, 363 ± 84) were different between the diets (P < .05), whereas no difference could be found for fat (carbohydrate-based diet, 820 ± 117; fat-based diet, 968 ± 136) and protein (carbohydrate-based diet, 252 ± 29; fat-based diet, 236 ± 23). However, during carbohydrate-based feeding, carbohydrate balance (288 ± 93 kcal/d) and fat balance (−327 ± 107 kcal/d) were significantly different from zero (P < .05), indicating continuous oxidation of endogenous fat and storage of administered glucose. During the fat-based diet, carbohydrate and fat balances were not different from zero. A correlation between energy and substrate balances was not seen during either diet. From these findings, it is concluded that (1) in patients with infections, up to 55% of energy intake can be given as fat; and (2) during feeding with the carbohydrate-based diet, a substantial part of the delivered glucose is stored as glycogen and endogenous fat is used for energy production." @default.
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• W2021106064 date "1992-02-01" @default.
• W2021106064 modified "2023-10-16" @default.
• W2021106064 title "Short-term energy balance in patients with infections: Carbohydrate-based versus fat-based diets" @default.
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• W2021106064 doi "https://doi.org/10.1016/0026-0495(92)90138-z" @default.
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