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- W2021107621 abstract "MicroRNAs (miRNAs) consist of a class of evolutionarily conserved small non‐coding RNA that regulates target messenger RNAs by mechanisms such as incomplete base pairing and post‐transcriptional gene silencing. Recent studies have shown that aberrant miRNA expression is a common feature of many human disorders including aging, heart diseases, cancer, autoimmune diseases and others. It seems likely that miRNA expression levels can be used as novel diagnostic markers. MiRNAs may also provide a new strategy for therapeutic interventions. In this review, we focus on recent advances in understanding how miRNA changes contribute to disease development and their potential as novel biomarkers and therapeutic targets for human diseases." @default.
- W2021107621 created "2016-06-24" @default.
- W2021107621 creator A5018665101 @default.
- W2021107621 creator A5044265790 @default.
- W2021107621 creator A5056656494 @default.
- W2021107621 date "2008-09-16" @default.
- W2021107621 modified "2023-10-18" @default.
- W2021107621 title "MicroRNA epigenetic alterations: predicting biomarkers and therapeutic targets in human diseases" @default.
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- W2021107621 doi "https://doi.org/10.1111/j.1399-0004.2008.01075.x" @default.
- W2021107621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18713257" @default.
- W2021107621 hasPublicationYear "2008" @default.
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