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- W2021112067 abstract "In view of the intrinsic defect in myocardial protein synthesis in the presence of acetaldehyde, the primary metabolite of ethanol, the effects of prolonged ethanol consumption on the hypertrophic response of the rat heart were studied. Changes in heart weight, myocardial protein and RNA content in response to banding of the ascending aorta were determined. Heart weight and heart to body weight ratios were reduced in non-banded ethanol diet animals when compared to nonbanded control diet rats. The extent of myocardial hypertrophy and the increment in RNA content resulting from banding were similar in both ethanol and control diet animals. These data indicate that although basal myocardial protein synthesis may be diminished in the alcoholic animal, the ability to respond in a compensatory manner to the stress imposed by aortic banding is retained." @default.
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- W2021112067 title "Effects of chronic ethanol consumption on the myocardial hypertrophic response to a pressure overload in the rat" @default.
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- W2021112067 doi "https://doi.org/10.1016/0022-2828(80)90008-5" @default.
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